Inflammatory skin Conditions Flashcards

1
Q

what do langerhans cells do?

A

antigen presenting cells

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2
Q

what is panniculitis?

A

inflammation in subcut fat

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3
Q

what is spongiotic epidermal reaction pattern

A

increase in space between cells because of oedema and lyphocytes

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4
Q

what is psoriasiform epidermal reaction pattern?

A

over growth of cells

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5
Q

what is bullous and pustular epidermal reaction pattern

A

bullous: large blister
pustular: with WBC

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6
Q

what to do if superficial lesions and not worried about it?

A

curettage

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7
Q

when use punch biopsy?

A

want get dx of an inflammatory condition

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8
Q

incisional biopsy for what?

A

blister
tumour

not for pigmented lesion

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9
Q

excisional biopsy for what?

A

something benign or even malignant

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10
Q

when do wide local excision?

A

after the dx from punch
remove scar
allow histologty
thicker tumour

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11
Q

PCR for what?

A

viruses
mycobacterium
monoclonal B and T lymphocytes

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12
Q

PAS stain for what?

A

fungi

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13
Q

spongiotic reactions seen in what?

A

allergic contact dermatitis
atopic dermatitis
drug reaction
fungal

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14
Q

what is parakeratosis?

A

nuclei in the keratinocytes in the outer layer of skin where there shouldn’t be.

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15
Q

ddx for psiorification?

A

Reiter’s
AIDS dermatitis
lichen simplex chronicus: (chornic rubbing)

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16
Q

what makes inclusion bodies in keratinocytes

A

viral infections

17
Q

CMV inclusion bodies look how?

A

like owl eyes, LARGE

18
Q

what to look out for in immunosuppressed person with skin issues?

A

CMV
VZV
infections

19
Q

non-blanching pupuric rash makes you thinking of what?

A

vasculitis

20
Q

2 layers of dermis

A

reticular (thicker collagen)

papillary (thinner collagen)