Inflammatory skin Conditions Flashcards
what do langerhans cells do?
antigen presenting cells
what is panniculitis?
inflammation in subcut fat
what is spongiotic epidermal reaction pattern
increase in space between cells because of oedema and lyphocytes
what is psoriasiform epidermal reaction pattern?
over growth of cells
what is bullous and pustular epidermal reaction pattern
bullous: large blister
pustular: with WBC
what to do if superficial lesions and not worried about it?
curettage
when use punch biopsy?
want get dx of an inflammatory condition
incisional biopsy for what?
blister
tumour
not for pigmented lesion
excisional biopsy for what?
something benign or even malignant
when do wide local excision?
after the dx from punch
remove scar
allow histologty
thicker tumour
PCR for what?
viruses
mycobacterium
monoclonal B and T lymphocytes
PAS stain for what?
fungi
spongiotic reactions seen in what?
allergic contact dermatitis
atopic dermatitis
drug reaction
fungal
what is parakeratosis?
nuclei in the keratinocytes in the outer layer of skin where there shouldn’t be.
ddx for psiorification?
Reiter’s
AIDS dermatitis
lichen simplex chronicus: (chornic rubbing)
what makes inclusion bodies in keratinocytes
viral infections
CMV inclusion bodies look how?
like owl eyes, LARGE
what to look out for in immunosuppressed person with skin issues?
CMV
VZV
infections
non-blanching pupuric rash makes you thinking of what?
vasculitis
2 layers of dermis
reticular (thicker collagen)
papillary (thinner collagen)
