Prostate cancer

Question 1

What is prostate cancer

Answer 1

1. most are adenocarcinomas
2. most found on peripheral zones of prostate
3. Prostatic intraepithelial neoplasia ( premalignanct lesion) progresses to prostate cancer
4. inactivation of p53 and PTEN genes

Question 2

Mestastatsis

Answer 2

Chest x ray
Bone scan
Pelvic MRI

Question 3

Prostate specific antigen ( Ivest)

Answer 3

PSA is elevated in cases of

• benign hyperplasia
• Prostate cancer
• urinary infection
• prostatitis

Question 4

Invest

Answer 4

• PSA levels

- Serum creatinine and renal ultrasound to ensure LUT are not due to renal obstruction

Question 5

Symptoms

Answer 5

1. Lower urinary tract symptoms
2. Haematospermia
3. Backache as a result of spinal metastasis