Congenital adrenal hyperplasia

Question 1

Congenital adrenal hyperplasia

Answer 1

• Group of inherited conditions where adrenal gland is larger than usual
• Body is missing enzyme ( 21 hydroxylase) which stimulates the larger adrenal glands to release cortisol

Question 2

Normal adrenal gland releases

Answer 2

• Mineralcorticoids
• Glucocorticoids
• Androgens

Question 3

Symptoms

Answer 3

• Salt wasting ( lethargy/vomitting, diarrhoea)
• Rapid growth/ precocious puberty
• Absent menstruation
• Prostatic enlargement/Cancer

Question 4

Pathophys

Answer 4

1. Disorder of 21 hydroxylase
2. Not enough aldosterone/cortisol release
3. Feedback
4. Excess testosterone produced
5. XX over virilisation, more masculine characteristics