Prostate Cancer Flashcards

1
Q

Most common type

Which zone of the prostate is it found

A

Adenocarcinoma

Peripheral zone

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2
Q

Most common in which race

A

african

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3
Q

Risk factors

A

Obesity
Family history
Increased testosterone

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4
Q

Symptoms

A
Frequency 
Urgency 
Hesitancy 
Nocturne
Poor stream
Terminal dribbling
WEIGHT LOSS + BONE PAIN --> Bone metastasis
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5
Q

What kind of bone metastasis do you get

A

OsteoSCLEROTIC

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6
Q

Investigations

A

PSA (not always elevated)

multiparametic MRI

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7
Q

What may be seen on biopsy

A

PIN- prostatic intra-epithelial neoplasia

ASAP- atypical small acinar proliferations

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8
Q

Treatment of organ confined disease

A

Radical surgery

Radical radiotherapy

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9
Q

Treatment of locally advanced disease

A

Radiotherapy with neo-adjuvant hormone therapy

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10
Q

Treatment of metastatic disease

A

Androgen deprivation (LHRH antagonists, anti-androgens)

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11
Q

When is hormone therapy solely indicated?

A

Symptomatic patients who are unfit for surgery

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12
Q

What scoring system is used

A

Gleasons score

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