Prostate Cancer Flashcards
Most common type
Which zone of the prostate is it found
Adenocarcinoma
Peripheral zone
Most common in which race
african
Risk factors
Obesity
Family history
Increased testosterone
Symptoms
Frequency Urgency Hesitancy Nocturne Poor stream Terminal dribbling WEIGHT LOSS + BONE PAIN --> Bone metastasis
What kind of bone metastasis do you get
OsteoSCLEROTIC
Investigations
PSA (not always elevated)
multiparametic MRI
What may be seen on biopsy
PIN- prostatic intra-epithelial neoplasia
ASAP- atypical small acinar proliferations
Treatment of organ confined disease
Radical surgery
Radical radiotherapy
Treatment of locally advanced disease
Radiotherapy with neo-adjuvant hormone therapy
Treatment of metastatic disease
Androgen deprivation (LHRH antagonists, anti-androgens)
When is hormone therapy solely indicated?
Symptomatic patients who are unfit for surgery
What scoring system is used
Gleasons score
