Benign Prostatic Hyperplasia Flashcards
1
Q
What is it
A
Hyperplasia of transitional zone of prostate due to imbalance between oestrogen and androgens
2
Q
What age range does it affect
A
Older men, typically over 50
3
Q
Risk factors
A
Hypertension + diabetes
4
Q
Symptoms
A
Hesitancy + terminal dribbling --> cardinal signs Others include: Nocturia Frequency Urgency Poor flow Haematuria Overflow incontinence
5
Q
What does prostate feel like on prostate exam
A
Smooth, regular + enlarged
“fixed craggy mass” = cancer
6
Q
Treatment if moderate-severe symptoms
A
Alpha blocker (end in ‘osin’ e.g. alfuzosin)
7
Q
Treatment if symptoms + prostate >30g or PSA >1.4
A
5-alpha reductase inhibitor (end in ‘ride’ e.g. finasteride)
8
Q
Treatment if severe symptoms + prostate >30g or PSA >1.4
A
Alpha blocker + 5-alpha reductase inhibitor
9
Q
Treatment if pharmacotherapy fails
A
TURP (trans-urethral resection of the prostate)
