Preseason 3 Flashcards
2 hours post-mi, what is expected morphology
Waviness of fibers at border of infarct
2 days post infarct
Coagulatiotn necrosis with neutrophilic infiltration
Aschoff bodies and what type of hypersensitiviy reaction
Acute rheumatic fever
type II
Remark/s on subacute infective endocarditis
Happens in left side of heart and in disesed valves
Can happen post-rheumatic fever
MCC: viridans, e.g. S sanguis
Pathology: irregular masses on the valve cusps that extend into the chordae
Remark/s on breast carcinoma in association with pericardial effusion
Associated with IHC of
(+) GATA-3 and mamaglobin
Small, warty vegetations along the lines of closure of valve leaflets
RHD
Large, irregular masses on the valve cusps that can extend onto the chordae
IE
Small, bland vegetations, usually attached at the line of closure
Non bacterial thrombotic endocarditis (NBTE)
Small or medium-sized vegetations on either or both sides of the valve leaflets
Libman-Sacks endocarditis
NBTE vegetations
Small, bland vegetations, usually attached at the line of closure
LSE vegtations
Small or medium-sized vegetations on either or both sides of the valve leaflets
Libman-Sacks endocarditis
RHD vegetaions
Small, warty vegetations along the lines of closure of valve leaflets
IE vegetations
Large, irregular masses on the valve cusps that can extend onto the chordae
B-cell lineage markers
CD 79a, CD 19
Tdt(+)
Lyphoid marker
Translocation of APML
T (15;17)
Myeloid markers
MPO, CD117, CD33
Remarks on CLL
Smudge cells
CD23(+)
CML
Low LAP score
Fish studies: (+) BCR-ABL1 t(9;22)
Types of hodgkin lymphoma
Mixed cellularity
Nodular sclerosis
Lymphocyte-depleted
Translocation of mantle cell lyphoma
T (11;14)
Case: no masses
Translocation of follicular lymphoma
t (14;18)
Remarks on burkitt lymphoma
Child
Starry sky pattern: sheets of medium-sized lymphocytes with several macrophages
T(8;14) cMYC
Ki77: 100%
Lymphoma of a patient with sjogren syndrome
Extranodal marginal zone lymphoma
CD20(+)
Pautrier microabscesses
Mycoses fungoides
(Cutaneous T cell lymphoma)
Biopsy: collection of cells with cerebriform nuclei (SEZARY CELLS) in the epidermis (PAUTRIER MICROABSCESSES)
Cd138+
Multiple myeloma
Pawn ball megakaryocytes
MDS
What is the most important differential diagnosis for essential thrombocytopenia?
Pre-fibrotic primary myelofibrosis, because survival of pre-fibrotic PMF patients are significantly shorter thatn that of ET patients
MULTIPLE myeloma’s crab
Hypercalcemia Renal failure Anemia Bone disease CD138
*the syndrome with hypocalcemia is diGeorge’s syndrome’s CATCH-22
**CREST syndrome’s C is Calcinosis
