Preseason 3

Question 1

2 hours post-mi, what is expected morphology

Answer 1

Waviness of fibers at border of infarct

Question 2

2 days post infarct

Answer 2

Coagulatiotn necrosis with neutrophilic infiltration

Question 3

Aschoff bodies and what type of hypersensitiviy reaction

Answer 3

Acute rheumatic fever

type II

Question 4

Remark/s on subacute infective endocarditis

Answer 4

Happens in left side of heart and in disesed valves
Can happen post-rheumatic fever
MCC: viridans, e.g. S sanguis
Pathology: irregular masses on the valve cusps that extend into the chordae

Question 5

Remark/s on breast carcinoma in association with pericardial effusion

Answer 5

Associated with IHC of

(+) GATA-3 and mamaglobin

Question 6

Small, warty vegetations along the lines of closure of valve leaflets

Answer 6

RHD

Question 7

Large, irregular masses on the valve cusps that can extend onto the chordae

Answer 7

IE

Question 8

Small, bland vegetations, usually attached at the line of closure

Answer 8

Non bacterial thrombotic endocarditis (NBTE)

Question 9

Small or medium-sized vegetations on either or both sides of the valve leaflets

Answer 9

Libman-Sacks endocarditis

Question 10

NBTE vegetations

Answer 10

Small, bland vegetations, usually attached at the line of closure

Question 11

LSE vegtations

Answer 11

Small or medium-sized vegetations on either or both sides of the valve leaflets
Libman-Sacks endocarditis

Question 12

RHD vegetaions

Answer 12

Small, warty vegetations along the lines of closure of valve leaflets

Question 13

IE vegetations

Answer 13

Large, irregular masses on the valve cusps that can extend onto the chordae

Question 14

B-cell lineage markers

Answer 14

CD 79a, CD 19

Question 15

Tdt(+)

Answer 15

Lyphoid marker

Question 16

Translocation of APML

Answer 16

T (15;17)

Question 17

Myeloid markers

Answer 17

MPO, CD117, CD33

Question 18

Remarks on CLL

Answer 18

Smudge cells

CD23(+)

Question 19

CML

Answer 19

Low LAP score

Fish studies: (+) BCR-ABL1 t(9;22)

Question 20

Types of hodgkin lymphoma

Answer 20

Mixed cellularity
Nodular sclerosis
Lymphocyte-depleted

Question 21

Translocation of mantle cell lyphoma

Answer 21

T (11;14)

Case: no masses

Question 22

Translocation of follicular lymphoma

Answer 22

t (14;18)

Question 23

Remarks on burkitt lymphoma

Answer 23

Child
Starry sky pattern: sheets of medium-sized lymphocytes with several macrophages
T(8;14) cMYC
Ki77: 100%

Question 24

Lymphoma of a patient with sjogren syndrome

Answer 24

Extranodal marginal zone lymphoma

CD20(+)

Question 25

Pautrier microabscesses

Answer 25

Mycoses fungoides
(Cutaneous T cell lymphoma)
Biopsy: collection of cells with cerebriform nuclei (SEZARY CELLS) in the epidermis (PAUTRIER MICROABSCESSES)

Question 26

Cd138+

Answer 26

Multiple myeloma

Question 28

Pawn ball megakaryocytes

Answer 28

MDS

Question 29

What is the most important differential diagnosis for essential thrombocytopenia?

Answer 29

Pre-fibrotic primary myelofibrosis, because survival of pre-fibrotic PMF patients are significantly shorter thatn that of ET patients

Question 30

MULTIPLE myeloma’s crab

Answer 30

Hypercalcemia
Renal failure
Anemia
Bone disease
CD138

*the syndrome with hypocalcemia is diGeorge’s syndrome’s CATCH-22

**CREST syndrome’s C is Calcinosis