Prematurity Flashcards
What are some complications of prematurity?
Respiratory distress syndrome Apnoea of prematurity Retinopathy of prematurity Necrotising enterocolitis Jaundice
What causes RDS?
Inadequate surfactant leading to high surface tension within alveoli –> atelectasis
What is the risk of RDS in infants ben at 26-28 and 30-31 weeks?
50%
25%
What is the presentation of RDS?
Tachypnoea
Intercostal recession
Expiratory grunting
Cyanosis
What is the investigation for RDS?
CXR-ground glass appearance with indistinct heart border
What is the prevention of RDS?
Maternal corticosteroids if premature labour likely
Try to prevent early labour
What is the management of RDS?
Oxygen
Assistent ventilation, preferably CPAP
Exogenous surfactant via ET tube
What are the complications of RDS?
Pneumothorax
Infection
Pulmonary haemorrhage
Chronic lung disease of prematurity
What is apnoea of prematurity?
Spontaneous cessation of breathing >20s, r shorter periods with oxygen desaturation or bradycardia
Seen in almost all neonates <28 weeks
What causes apnoea of prematurity?
Immaturity of autonomic nervous system
What is the management of apnoea of prematurity?
Apnoea monitoring
Tactile stimulation
IV caffeine
What is retinopathy of prematurity?
Abnormal development of blood vessels in retina due to prematurity –> scarring, retinal detachment and blindness
Occurs in babies <32 weeks
What is the management of retinopathy of prematurity?
Laser photocoagulation
What are the risk factors for necrotising enterocolitis?
Very low birthweight Very premature RDS, assisted ventilation Sepsis Congenital heart disease
What is the presentation of necrotising enterocolitis?
Usually 2nd week of life Intolerant to feeds Bilious vomiting Distended, tender abdomen Absent bowel sounds Blood in stool