Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Paeds AM > Glomerulonephritis > Flashcards

Glomerulonephritis Flashcards

1
Q

What ae some causes of nephritic syndrome in children?

A

IgA neohropathy
Alport syndrome
Lupus nephritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are some causes of nephrotic syndrome in kids?

A

Minimal change disease

Focal segmental glomerulosclerosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are some causes of mixed disease in kids?

A

Post strep glomerulonephritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What causes IgA nephropathy?

A

Most common cause of glomerulonephritis

IgA deposition causing increased proliferation of mesangial cells and clogging of tubules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is IgA nephropathy associated with?

A

Henosh-Schonlein purpura aka IgA vasculitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What triggers Henoch-Schonlein purple?

A

Viral URTI, drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the presentation of IgA nephropathy?

A

Macroscopic haematuria in young person 1-2 days post URTI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What investigations are done for IgA nephropathy?

A

Urinalysis- haematuria and light proteinuria

FBC, U&Es

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the management of IgA nephropathy?

A

Usually self limiting- supportive

Corticosteroids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is Alport syndrome?

A

Genetic disorder of glomerulonephritis and hearing loss

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the presentation of Alport syndrome?

A

Early haematuria
Late proteinuria
Hearing loss
Eye changes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the most common cause of lupus nephritis?

A

Class IV- most severe

Diffuse proliferative nephritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the presentation of lupus nephritis?

A

Nephritic syndrome

AKI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What investigations are done for lupus nephritis?

A

Urinalysis- red blood cell casts, haematuria, proteinuria

FBC, U&Es, autoantibodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the management of lupus nephritis?

A

Immunosuppression

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What causes post strep glomerulonephritis?

A

Immune complex deposition in glomeruli

17
Q

What is the presentation of post strep glomerulonephritis?

A

7-14 days post strep infection, usually strep pyogenes
Microscopic haematuria, large vol proteinuria
Headache, malaise

18
Q

What is the management of post strep GN?

A

Antibiotics if infection still present
Loop diuretics
Vasodilators

19
Q

What is the prognosis for post strep glomerulonephritis?

A

80% make full recovery

Complications- hypertension, oedema

20
Q

What is nephrotic syndrome?

A

Triad of proteinuria >3g/24 hours, hypoalbumnaemia <30, oedema

21
Q

What is minimal change disease?

A

Most common cause of nephrotic syndrome in children and young people

22
Q

What causes minimal change disease?

A

NSAIDs

Hpdgkin’s

23
Q

What is the classic presentation of minimal change disease?

A

2-5yo with sudden onset oedema, proteinuria and low albumin

24
Q

What is the management of minimal change disease?

A

High dose corticosteroids for 4 weeks, then slow taper over 8 weeks

25
Q

What is the management of relapses of minimal change disease?

A

Immunosuppression

26
Q

What is the prognosis for minimal change disease?

A

Relapses but overall good prognosis

Paeds AM (28 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions