Prasugrel

Question 0

What is often used prasugrel often used for

Answer 0

Reduction of stent thrombosis and other events when stent has be used because of acute coronary syndrome

Question 1

What is another name for prasugrel

Answer 1

Effient

Question 2

How is prasugrel administered

Answer 2

Orally

Question 3

What’s the major difference between prasugrel and clopidogrel

Answer 3

Prasugrel is broken down in a single step by a more common enzyme CYP34A and CYP2B6… In a lesser amount 2C9 and 19.

Question 4

What is another get thing about prasugrel

Answer 4

No drug interactions ESP with P450 inhibitors or inducers

Question 5

Like clopidogrel, prasugrel also has a black box warning. Why.

Answer 5

It can cause major bleeding and at a higher rate than other drugs in this category

Question 6

Because of the black box warning label prasugrel has, what type of patients should we carefully monitor

Answer 6

Those below 60kg give a lower dose because they are at a higher risk for bleeding; a daily dose of about 5 or 10mg is good

Question 7

What’s one good thing about prasugrel pk action

Answer 7

Predictable inhibition of ADP induced platelet aggregation

Question 8

What 3 types of patients should avoid taking prasugrel

Answer 8

Patients with ischemic attack
Stroke- increases incidence
Urgent need for surgery like coronary bypass graft surgery

Question 9

I’m some rare cases what can prasugrel cause

Answer 9

Thrombotic thrombocytopenic purpura

Question 10

What is pci

Answer 10

Find answer