Abciximab Flashcards
0
Q
Why is the mechanism of action for abciximab
A
It’s a monoclonal antibody that attaches to GP 2b/3a receptor
1
Q
What is another name for abciximab
A
Reopro
2
Q
Why is abciximab so effective
A
Because it stops platelet aggregation by stopping binding of fibrogen, vWF, and adhesive molecule to the receptors
3
Q
How is abciximab administered
A
By IV bolus
4
Q
What is the half life of abciximab
A
Unbound it’s 30 min but bound to the Gb 2b/3a receptor 18-24 hr after infusion has ended
5
Q
What is bad about abciximab
A
It’s expensive about 1,500 bucks per shot
6
Q
What is abciximab used in conjunction with
A
Warfarin and aspirin
7
Q
What is use of abciximab
A
For prevention of restonosis another heart attack and coronary thrombosis for angioplasty
