Argatroban Flashcards
1
Q
What is argatroban
A
a direct thrombin 2a inhibitor
2
Q
What are indications for argatroban
A
used for patients with HIT
used for patients with angioplasty w/ HIT or at risk for HIT
3
Q
How is argatroban administered
A
IV for immediate onset
4
Q
Where is argatroban metabolized
A
in the liver
5
Q
What test is used to monitor argatroban
A
aPTT at base line
monitor hemoglobin and hematocrit
6
Q
What is the major side effect of argatroban
A
bleeding
7
Q
Who is contraindicated or must be watched closely on
A
use cautiously in patients with liver impairment; decrease dose
