Practice Questions Test 2 Flashcards by Preeti Gulve

Hypercalcemia of malignancy

and

Ingestion of Centrum Diurnum

can cause what affect?

Mineralization of soft tissues

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What is the most reliable indicator of malignant phenotype?

Metastasis

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How do you identify that a

distended stomach

was from pre-mortem bloat and NOT

post-mortem change?

Look for a

bloat line

in the distal esophagus

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What is the etiology and EDx in this tissue from a horse?

Etiology: NSAIDS

EDx: Drug induced nephritis

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The formation of abundant collagenous stroma in response to the presence of certain kinds of carcinomas and adenocarcinomas is referred to as

Desmoplasia

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What is the etiology of this tissue from a horse?

Strongylus vulgaris

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What is the MDx (morphologic diagnosis)

of this tissue from a horse?

Focal chronic arteritis

with

aneurysm and thrombosis

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What is the etiologic diagnosis of this tissue from a horse?

Verminous arteritis

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You are presented a Lutino Turquoise parrot with raised firm/hard periarticular masses on the dorsal aspect of left foot. On biopsy, masses are composed of white chalky material interpreted as tophy. What is the name of the condition?

Articular gout

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This affected area most likely will heal by:

Fibrosis

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The MAIN function of this mediator of inflammation is to induce vasodilation and heat at a site of acute inflammation

Nitric Oxide

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What is the

morphologic diagnosis

in this tissue from an ox?

Acute, severe, diffuse fibrinous pleuritis and pleural effusion

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What does “p53”

aka “guardian of the genome” do?

Stops cell cycle

and

initiates apoptosis

in response to

irreparable DNA damage

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The usual cause of chronic hepatic congestion (“nutmeg liver”) is?

Right-sided congestive heart failure

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T/F:

Omega 6 Fatty Acids-derived eicosinoids are beneficial in inflammation

FALSE

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What is the major activator of

macrophages

chronic inflammation?

IFN-gamma

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T/F:

Hyperfibrinogenemia may precede neutrophilia in acute inflammatory process in cattle and horses

TRUE

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T/F:

Mycobacterium tuberculosis

in cows

is associated with

fibrinous inflammation

FALSE

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T/F:

Gallid-herpesvirus-1

is associated with

fibrinous inflammation

TRUE

T/F:

Heat in the upper airways of any species

is associated with

fibrinous inflammation

TRUE

T/F:

Haemophilis parasuis in pigs

is associated with fibrinous inflammation

TRUE

T/F:

Mannheimia haemolytica

in cattle is associated with

fibrinous inflammation

TRUE

What’s this called?

Pyometra

What is the morphologic diagnosis?

Acute, severe, suppurative metritis

The most likely diagnosis for the ulcerative and destructive lesion in the ear of this cat is?

Squamous cell carcinoma

Intact basement membrane of alveolar walls with damaged type II pneumocytes and Failure of phagocytic cells to remove fibrin in alveolar interstitium call lead to the development of this type of fibrosis

Intraalveolar fibrosis

T/F: Cachexia is considered a paraneoplastic syndrome

TRUE

T/F: Cachexia is pathognomonic for hemangiomas

FALSE

T/F: Cachexia is seen in chronic inflammatory processes

TRUE

T/F: There is atrophy of muscles in Cachexia

TRUE

What is cachexia?

General physical wasting with loss of weight and muscle mass due to a disease.

What is the etiologic diagnosis (EDx) for this tissue from a pig?

Lawsonial enteritis

What is the the most important growth factor for angiogenesis?

VEGF

Development of Scurvy, Bleeding at joints, and Delayed healing may develop in guinea pigs deficient in what?

Vitamin C!

Which of the following is the most important feature that distinguish a thrombus from a postmortem clot?

Attachment to the vessel wall POSTmortem clots are NOT attached

T/F: Exudates Have low cellular content Have low protein content Have low specific gravity

FALSE Exudates have HIGH cellular content, protein content, and specific gravity

T/F: Exudates Result from decreased oncotic pressure

FALSE Exudates result from INCREASED oncotic pressure

T/F: Exudates result from lymphatic obstruction

FALSE

Which material or pigment is found within the cytoplasm of “heart failure cells”?

Hemosiderin

The medical term used to indicate pathological coagulation of blood is?

Thrombosis

What is this condition called?

Brachygnathia Abnormal shortness or recession of the mandible (lower jaw)

Which type of tumor exhibits neoplastic cells of both mesenchymal and epithelial origin?

Nephroblastoma

The preferred pathway of spread for malignant tumors will depend on several factors including topographic location and whether they are from epithelial or mesenchymal origin. Which of the following tumors is most likely to spread initially through the lymphatics?

Ocular Squamous Cell Carcinoma

Which picture represents an acute lesion?

The most effective anti-tumor mechanisms in the host are mediated primarily by:

CD8+ Cytotoxic T-lymphocytes

Nodular dermatofibrosis in German Shepherd dogs is characterized by neoplastic lesions in:

The kidney

In dogs, hypercalcemia of malignancy, a paraneoplastic syndrome, is often associated with which two tumors?

Lymphosarcomas and Anal sac carcinomas