Practice Questions Test 2 Flashcards
Hypercalcemia of malignancy
and
Ingestion of Centrum Diurnum
can cause what affect?
Mineralization of soft tissues
What is the most reliable indicator of malignant phenotype?
Metastasis
How do you identify that a
distended stomach
was from pre-mortem bloat and NOT
post-mortem change?
Look for a
bloat line
in the distal esophagus
What is the etiology and EDx in this tissue from a horse?
Etiology: NSAIDS
EDx: Drug induced nephritis
The formation of abundant collagenous stroma in response to the presence of certain kinds of carcinomas and adenocarcinomas is referred to as
Desmoplasia
What is the etiology of this tissue from a horse?
Strongylus vulgaris
What is the MDx (morphologic diagnosis)
of this tissue from a horse?
Focal chronic arteritis
with
aneurysm and thrombosis
What is the etiologic diagnosis of this tissue from a horse?
Verminous arteritis
You are presented a Lutino Turquoise parrot with raised firm/hard periarticular masses on the dorsal aspect of left foot. On biopsy, masses are composed of white chalky material interpreted as tophy. What is the name of the condition?
Articular gout
This affected area most likely will heal by:
Fibrosis
The MAIN function of this mediator of inflammation is to induce vasodilation and heat at a site of acute inflammation
Nitric Oxide
What is the
morphologic diagnosis
in this tissue from an ox?
Acute, severe, diffuse fibrinous pleuritis and pleural effusion
What does “p53”
aka “guardian of the genome” do?
Stops cell cycle
and
initiates apoptosis
in response to
irreparable DNA damage
The usual cause of chronic hepatic congestion (“nutmeg liver”) is?
Right-sided congestive heart failure
T/F:
Omega 6 Fatty Acids-derived eicosinoids are beneficial in inflammation
FALSE
What is the major activator of
macrophages
in
chronic inflammation?
IFN-gamma
T/F:
Hyperfibrinogenemia may precede neutrophilia in acute inflammatory process in cattle and horses
TRUE
T/F:
Mycobacterium tuberculosis
in cows
is associated with
fibrinous inflammation
FALSE
T/F:
Gallid-herpesvirus-1
is associated with
fibrinous inflammation
TRUE
T/F:
Heat in the upper airways of any species
is associated with
fibrinous inflammation
TRUE
T/F:
Haemophilis parasuis in pigs
is associated with fibrinous inflammation
TRUE
T/F:
Mannheimia haemolytica
in cattle is associated with
fibrinous inflammation
TRUE
What’s this called?
Pyometra
What is the morphologic diagnosis?
Acute, severe, suppurative metritis
The most likely diagnosis for the ulcerative and destructive lesion in the ear of this cat is?
Squamous cell carcinoma
Intact basement membrane of alveolar walls with damaged type II pneumocytes
and
Failure of phagocytic cells to remove fibrin in alveolar interstitium
call lead to the development of this type of fibrosis
Intraalveolar fibrosis
T/F:
Cachexia is considered a paraneoplastic syndrome
TRUE
T/F:
Cachexia is pathognomonic for hemangiomas
FALSE
T/F:
Cachexia is seen in chronic inflammatory processes
TRUE
T/F:
There is atrophy of muscles in Cachexia
TRUE
What is cachexia?
General physical wasting with loss of weight and muscle mass due to a disease.
What is the etiologic diagnosis (EDx)
for this tissue from a pig?
Lawsonial enteritis
What is the the most important growth factor for angiogenesis?
VEGF
Development of Scurvy,
Bleeding at joints,
and
Delayed healing
may develop in guinea pigs deficient in what?
Vitamin C!
Which of the following is the most important feature that distinguish a thrombus from a postmortem clot?
Attachment to the vessel wall
POSTmortem clots are NOT attached
T/F:
Exudates
Have low cellular content
Have low protein content
Have low specific gravity
FALSE
Exudates have
HIGH cellular content, protein content, and specific gravity
T/F:
Exudates
Result from decreased oncotic pressure
FALSE
Exudates result from
INCREASED
oncotic pressure
T/F:
Exudates result from lymphatic obstruction
FALSE
Which material or
pigment is found within the cytoplasm of
“heart failure cells”?
Hemosiderin
The medical term used to indicate pathological coagulation of blood is?
Thrombosis
What is this condition called?
Brachygnathia
Abnormal shortness or recession of the mandible (lower jaw)
Which type of tumor exhibits neoplastic cells of both
mesenchymal and epithelial origin?
Nephroblastoma
The preferred pathway of spread for malignant tumors will depend on several factors including topographic location and whether they are from epithelial or mesenchymal origin. Which of the following tumors is most likely to spread initially through the lymphatics?
Ocular Squamous Cell Carcinoma
Which picture represents an
acute lesion?
The most effective anti-tumor mechanisms in the host are mediated primarily by:
CD8+ Cytotoxic T-lymphocytes
Nodular dermatofibrosis in German Shepherd dogs is characterized by neoplastic lesions in:
The kidney
In dogs, hypercalcemia of malignancy, a paraneoplastic syndrome, is often associated with which two tumors?
Lymphosarcomas
and
Anal sac carcinomas
