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RUSVM Pathology 3rd Semester > Practice Questions Test 2 > Flashcards

Practice Questions Test 2 Flashcards

1
Q

Hypercalcemia of malignancy

and

Ingestion of Centrum Diurnum

can cause what affect?

A

Mineralization of soft tissues

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2
Q

What is the most reliable indicator of malignant phenotype?

A

Metastasis

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3
Q

How do you identify that a

distended stomach

was from pre-mortem bloat and NOT

post-mortem change?

A

Look for a

bloat line

in the distal esophagus

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4
Q

What is the etiology and EDx in this tissue from a horse?

A

Etiology: NSAIDS

EDx: Drug induced nephritis

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5
Q

The formation of abundant collagenous stroma in response to the presence of certain kinds of carcinomas and adenocarcinomas is referred to as

A

Desmoplasia

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6
Q

What is the etiology of this tissue from a horse?

A

Strongylus vulgaris

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7
Q

What is the MDx (morphologic diagnosis)

of this tissue from a horse?

A

Focal chronic arteritis

with

aneurysm and thrombosis

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8
Q

What is the etiologic diagnosis of this tissue from a horse?

A

Verminous arteritis

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9
Q

You are presented a Lutino Turquoise parrot with raised firm/hard periarticular masses on the dorsal aspect of left foot. On biopsy, masses are composed of white chalky material interpreted as tophy. What is the name of the condition?

A

Articular gout

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10
Q

This affected area most likely will heal by:

A

Fibrosis

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11
Q

The MAIN function of this mediator of inflammation is to induce vasodilation and heat at a site of acute inflammation

A

Nitric Oxide

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12
Q

What is the

morphologic diagnosis

in this tissue from an ox?

A

Acute, severe, diffuse fibrinous pleuritis and pleural effusion

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13
Q

What does “p53”

aka “guardian of the genome” do?

A

Stops cell cycle

and

initiates apoptosis

in response to

irreparable DNA damage

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14
Q

The usual cause of chronic hepatic congestion (“nutmeg liver”) is?

A

Right-sided congestive heart failure

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15
Q

T/F:

Omega 6 Fatty Acids-derived eicosinoids are beneficial in inflammation

A

FALSE

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16
Q

What is the major activator of

macrophages

in

chronic inflammation?

A

IFN-gamma

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17
Q

T/F:

Hyperfibrinogenemia may precede neutrophilia in acute inflammatory process in cattle and horses

A

TRUE

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18
Q

T/F:

Mycobacterium tuberculosis

in cows

is associated with

fibrinous inflammation

A

FALSE

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19
Q

T/F:

Gallid-herpesvirus-1

is associated with

fibrinous inflammation

A

TRUE

20
Q

T/F:

Heat in the upper airways of any species

is associated with

fibrinous inflammation

A

TRUE

21
Q

T/F:

Haemophilis parasuis in pigs

is associated with fibrinous inflammation

A

TRUE

22
Q

T/F:

Mannheimia haemolytica

in cattle is associated with

fibrinous inflammation

A

TRUE

23
Q

What’s this called?

A

Pyometra

24
Q

What is the morphologic diagnosis?

A

Acute, severe, suppurative metritis

25
Q

The most likely diagnosis for the ulcerative and destructive lesion in the ear of this cat is?

A

Squamous cell carcinoma

26
Q

Intact basement membrane of alveolar walls with damaged type II pneumocytes

and
Failure of phagocytic cells to remove fibrin in alveolar interstitium

call lead to the development of this type of fibrosis

A

Intraalveolar fibrosis

27
Q

T/F:

Cachexia is considered a paraneoplastic syndrome

A

TRUE

28
Q

T/F:

Cachexia is pathognomonic for hemangiomas

A

FALSE

29
Q

T/F:

Cachexia is seen in chronic inflammatory processes

A

TRUE

30
Q

T/F:

There is atrophy of muscles in Cachexia

A

TRUE

31
Q

What is cachexia?

A

General physical wasting with loss of weight and muscle mass due to a disease.

32
Q

What is the etiologic diagnosis (EDx)

for this tissue from a pig?

A

Lawsonial enteritis

33
Q

What is the the most important growth factor for angiogenesis?

A

VEGF

34
Q

Development of Scurvy,

Bleeding at joints,

and
Delayed healing

may develop in guinea pigs deficient in what?

A

Vitamin C!

35
Q

Which of the following is the most important feature that distinguish a thrombus from a postmortem clot?

A

Attachment to the vessel wall

POSTmortem clots are NOT attached

36
Q

T/F:

Exudates

Have low cellular content
Have low protein content
Have low specific gravity

A

FALSE

Exudates have

HIGH cellular content, protein content, and specific gravity

37
Q

T/F:

Exudates

Result from decreased oncotic pressure

A

FALSE

Exudates result from

INCREASED

oncotic pressure

38
Q

T/F:

Exudates result from lymphatic obstruction

A

FALSE

39
Q

Which material or
pigment is found within the cytoplasm of
“heart failure cells”?

A

Hemosiderin

40
Q

The medical term used to indicate pathological coagulation of blood is?

A

Thrombosis

41
Q

What is this condition called?

A

Brachygnathia

Abnormal shortness or recession of the mandible (lower jaw)

42
Q

Which type of tumor exhibits neoplastic cells of both

mesenchymal and epithelial origin?

A

Nephroblastoma

43
Q

The preferred pathway of spread for malignant tumors will depend on several factors including topographic location and whether they are from epithelial or mesenchymal origin. Which of the following tumors is most likely to spread initially through the lymphatics?

A

Ocular Squamous Cell Carcinoma

44
Q

Which picture represents an

acute lesion?

A
45
Q

The most effective anti-tumor mechanisms in the host are mediated primarily by:

A

CD8+ Cytotoxic T-lymphocytes

46
Q

Nodular dermatofibrosis in German Shepherd dogs is characterized by neoplastic lesions in:

A

The kidney

47
Q

In dogs, hypercalcemia of malignancy, a paraneoplastic syndrome, is often associated with which two tumors?

A

Lymphosarcomas

and

Anal sac carcinomas

RUSVM Pathology 3rd Semester (12 decks)

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