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RUSVM Pathology 3rd Semester > Example Test Questions Test 2 > Flashcards

Example Test Questions Test 2 Flashcards

1
Q

In Congenital Bovine Porphyria

which tissues may fluoresce red under UV light?

A

teeth, bones

kidney, lungs

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2
Q

T/F:

Centrifugation can be used to differentiate between

hematuria and hemoglobinuria.

In hematuria, precipitation will form at the bottom of the tube unlike hemoglobinuria

A

TRUE

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3
Q

T/F:

Physiological hemorrhages occur during inflammation

A

FALSE

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4
Q

If during necropsy, you see focal blood spots less than 2mm

in diameter on the mucosa of the lower jejunum,

how would you classify them?

A

petechiae

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5
Q

What three reasons are associated with slow wound healing?

A

Foreign body rxn to sutures

Malnutrition

Infection

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6
Q

T/F:

Epitheloid cells may coalesce to form multinucleated giant cells like Langhan’s giant cell, which is identified by the arrangement of nuclei around the periphery of the cell

A

TRUE

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7
Q

Which of the following has the least capacity for regeneration?

cardiac muscle

bone

liver parenchyma

squamous epithelium

fibrous connective tissue

A

cardiac muscle

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8
Q

T/F:

Patients with disseminated intravascular coagulation (DIC)

may develop both microthrombosis and hemorrhage in many tissues

A

TRUE

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9
Q

Death from shock is largely due to ischemia of what 2 organs?

A

Myocardial ischemia

Cerebral ischemia

(heart and brain)

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10
Q

Which are not intravascular inflammatory cells?

neutrophils and lymphocytes

epitheloid cells and macrophages

eosinophils and basophils

plasma cells and monocytes

monocytes and platelets

A

epitheloid cells and macrophages

(monocytes are circulating, macrophages are in tissue)

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11
Q

Which of these is not characteristic of chronic inflammation?

macrophages

plasma cells

Langhan’s giant cells

Fibroblasts

Neutrophils

A

Neutrophils

are characteristic of acute inflammation, not chronic

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12
Q

What 2 things are granulation tissue mainly composed of?

A

Angioblasts and Fibroblasts

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13
Q

T/F:

Cellulitis is a diffuse suppurative lesion without a connective tissue capsule and commonly seen in subQ tissue and fascial planes of muscles

A

TRUE

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14
Q

T/F:

Neutrophils fuse together to form foreign body giant cells in a granulomatous inflammation caused by foreign bodies,

or to form Langhan’s giant cells in tuberculosis

A

FALSE!

MACROPHAGES fuse together!

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15
Q

Which of these mediators is preformed in mast cells?

histamine

leukotriene

nitric oxide

prostaglandin

complements

A

histamine

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16
Q

Excessive granulation tissue in the skin of an equine may result in

A

proud flesh

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17
Q

The least important feature of neoplastic malignancy is:

High mitotic index

Anaplasia

Metastasis

Cellular differentiation

A

cellular differentiation

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18
Q

Empyema has the same type of exudate as:

Abscess

Tuberculosis

Granuloma

Hydromyelia

A

abscess

(purulent)

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19
Q

Healing of a deep and wide skin ulcer will most likely be by:

regeneration

replacement with fibrous tissue

replacement with fibrinous tissue

primary union

A

replacement with FIBROUS tissue

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20
Q

Some neoplasms are difficult to categorize into either carcinoma or sarcoma. The best example of such a neoplasm is:

Lymphosarcoma

Malignant hepatoma

Malignant melanoma

Carcinoma-in-situ

A

malignant melanoma

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21
Q

T/F:

Hydraencephaly is excessive accumulation of fluid in the ventricles of the brain

A

FALSE!

hydrocephalus is in the ventricles

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22
Q

On histological examination, a lesion of bovine small intestine revealed a simple granuloma which contained acid-fast bacilli.

The lesion was most likely caused by:

  • streptococcus spp.*
  • mycobacterium bovis*
  • corynebacterium pseudotuberculosis*
  • mycobacterium paratuberculosis*
A

mycobacterium paratuberculosis

(Johne’s disease)

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23
Q

Replacement of dead cells cannot occur by regeneration in tissues composed of:

labile cells

stable cells

permanent cells

stem cells

A

permanent cells

24
Q

Wound contraction is primarily mediated by:

smooth muscle cells

macrophages

fibrin

myofibroblasts

A

myofibroblasts

25
Q

Fat necrosis is often associated with:

acute hepatitis

a high calorie diet

acute pancreatitis

acute splenitis

A

acute pancreatitis

26
Q

T/F:

In the sequence of leukocyte events in inflammation caused by staphylococcus aureus, the leukocytes attach to endothelium, then transmigrate through the interendothelial junctions, pierce the vascular basement membrane, and migrate along a concentration gradient of inflammatory mediator

A

TRUE

27
Q

You were invited to St. Kitts to perform necropsy on an old cow. You observed several discrete lesions measuring between 2 and 5 cm in diameter in the lungs only. On cross section of the lesions, you heard gritty sound and observed cheese-like pale content. Bacteriology of several lesions yielded pure growth of mycobacterium bovis.

What is the MDx?

A

Tuberculosis (granulomatous) pneumonia

28
Q

You were invited to St. Kitts to perform necropsy on an old cow. You observed several discrete lesions measuring between 2 and 5 cm in diameter in the lungs only. On cross section of the lesions, you heard gritty sound and observed cheese-like pale content. Bacteriology of several lesions yielded pure growth of mycobacterium bovis​.

Histopathologically, the most predominant inflammatory cells in the lesions would be?

A

Macrophages, epitheloid cells, Langhan’s giant cells, and fibroblasts

29
Q

You were invited to St. Kitts to perform necropsy on an old cow. You observed several discrete lesions measuring between 2 and 5 cm in diameter in the lungs only. On cross section of the lesions, you heard gritty sound and observed cheese-like pale content. Bacteriology of several lesions yielded pure growth of mycobacterium bovis​.

The inflammation could be classified as?

A

CHRONIC

(because granulomatous)

30
Q

T/F:

The presence of a disease process (type of neoplasm or abscess) at a site distant from the site of origin is known as metastasis

A

TRUE!

(yes, even an abscess)

31
Q

Which of these infectious agents can cause

bovine cerebellar hypoplasia**?

Rabies Virus

Bovine Viral Diarrhea

Staphylococcus aureus

Bovine Papilloma Virus

A

bovine viral diarrhea

32
Q

T/F:

A neoplasm is an inflammatory lesion

A

FALSE

not inflammatory

33
Q

T/F:

Carcinoma-in-situ refers to a malignant neoplasm of epithelial origin that has not penetrated the basement membrane

A

TRUE

34
Q

What type of exudates occurs commonly in parasite infestation?

Purulent

Hemorrhagic

Eosinophilic

Lymphocytic

A

eosinophilic

35
Q

A pseudomembrane is what type of exudate?

Purulent

Fibrous

Serous

Fibrinous

A

fibrinous

36
Q

What is the special stain for the fibrinous exudate pseudomembrane on the intestine?

A

PTAH

37
Q

If fibrinous tissue pseudomembrane organizes, what tissue replaces it?

A

FIBROUS tissue

38
Q

Anthrax infection

is associated with what exudative inflammatory response?

A

Hemorrhagic inflammation

39
Q

Diphtheritic enteritis

is associated with what exudative inflammatory response?

A

Fibrinous inflammation

40
Q

Rabies infection

is associated with what exudative inflammatory response?

A

Lymphocytic inflammation

41
Q

Mycobacterium paratuberculosis

is associated with what exudative inflammatory response?

A

Granulomatous inflammation

(chronic, Johne’s DZ)

42
Q

Phlegmonous pneumonia

is associated with what exudative inflammatory response?

A

purulent inflammation

43
Q

T/F:

The major processes of inflammation include:

Increased blood flow

Lekocyte exudation

Increased vascular permeability

A

TRUE

44
Q

Helminth parasite associated with animal neoplasia in St. Kitts dogs is:

A

Spirocerca

(osteosarcoma)

45
Q

Exudation in ACUTE inflammation includes all of the following EXCEPT:

Serous

Fibrinous

Fibrinopurulent

Suppurative

Epitheloid

A

epitheloid is chronic

other chronic types of inflammation include

(**fibrous **and granulomatous)

46
Q

The majority of CHRONIC inflammatory responses are dependent PRIMARILY on:

Macrophages

Blood vessels

Collagen

Macrophages and fibroblasts

Fibroplasia

A

Macrophages AND** fibroblasts**

47
Q

The most predominant cell in non-suppurative inflammation is:

Polymorphonuclear cells

Lymphocytes

Monocytes

Macrophages

None of the above/Not a true statement

A

lymphocytes

48
Q

Transforms into another type of cell outside blood vessels:

Polymorphonuclear cells

Lymphocytes

Monocytes

Macrophages

None of the above/Not a true statement

A

monocytes

49
Q

The precursor of plasma cells:

Polymorphonuclear cells

Lymphocytes

Monocytes

Macrophages

None of the above/Not a true statement

A

lymphocytes

(b-cells, b-lymphocytes)

50
Q

Polymorphonuclear cells include epitheloid cells:

Polymorphonuclear cells

Lymphocytes

Monocytes

Macrophages

None of the above/Not a true statement

A

none of the above

polymorphonuclear cells only include neutrophils. basophils, eosinophils, and mast cells

Epitheloid cells are mononuclear and include monocytes and macrophages, platelets, plasma cells, and lymphocytes

51
Q

Most important in inflammatory leukocyte exudation:

Polymorphonuclear cells

Lymphocytes

Monocytes

Macrophages

None of the above/Not a true statement

A

Polymorphonuclear cells

neutrophils

52
Q

Most important in formation of giant cells in some types of granulomas:

Polymorphonuclear cells

Lymphocytes

Monocytes

Macrophages

None of the above/Not a true statement

A

Macrophages

53
Q

A condition characterized by a reduction in tissue perfusion and oxygen delivery below the levels required to meet normal demands is the definition for:

A

SHOCK

54
Q

An ACUTE inflammatory response is dependent on:

Neutrophils

Bacteria

Blood vessels

Mediators

A

blood vessels

55
Q

Which is the most important factor that promotes thrombosis?

Sluggish blood flow

Endothelial injury

Increased blood flow

Increased blood coagulability

Adenoma

A

endothelial injury

56
Q

Gram negative bacteria are a major cause of which type of shock?

A

septic shock

57
Q

The 2 basic mechanisms that can lead to development of DIC

(disseminated intravascular coagulation) include:

Massive release of tissue thromboplastin in circulation

Widespread injury to capillary endothelial cells

Thrombocytopenia and injury to aorta

A

Massive release of tissue thromboplastin in circulation

Widespread injury to capillary endothelial cells

RUSVM Pathology 3rd Semester (12 decks)

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