Example Test Questions Test 2 Flashcards
In Congenital Bovine Porphyria
which tissues may fluoresce red under UV light?
teeth, bones
kidney, lungs
T/F:
Centrifugation can be used to differentiate between
hematuria and hemoglobinuria.
In hematuria, precipitation will form at the bottom of the tube unlike hemoglobinuria
TRUE
T/F:
Physiological hemorrhages occur during inflammation
FALSE
If during necropsy, you see focal blood spots less than 2mm
in diameter on the mucosa of the lower jejunum,
how would you classify them?
petechiae
What three reasons are associated with slow wound healing?
Foreign body rxn to sutures
Malnutrition
Infection
T/F:
Epitheloid cells may coalesce to form multinucleated giant cells like Langhan’s giant cell, which is identified by the arrangement of nuclei around the periphery of the cell
TRUE
Which of the following has the least capacity for regeneration?
cardiac muscle
bone
liver parenchyma
squamous epithelium
fibrous connective tissue
cardiac muscle
T/F:
Patients with disseminated intravascular coagulation (DIC)
may develop both microthrombosis and hemorrhage in many tissues
TRUE
Death from shock is largely due to ischemia of what 2 organs?
Myocardial ischemia
Cerebral ischemia
(heart and brain)
Which are not intravascular inflammatory cells?
neutrophils and lymphocytes
epitheloid cells and macrophages
eosinophils and basophils
plasma cells and monocytes
monocytes and platelets
epitheloid cells and macrophages
(monocytes are circulating, macrophages are in tissue)
Which of these is not characteristic of chronic inflammation?
macrophages
plasma cells
Langhan’s giant cells
Fibroblasts
Neutrophils
Neutrophils
are characteristic of acute inflammation, not chronic
What 2 things are granulation tissue mainly composed of?
Angioblasts and Fibroblasts
T/F:
Cellulitis is a diffuse suppurative lesion without a connective tissue capsule and commonly seen in subQ tissue and fascial planes of muscles
TRUE
T/F:
Neutrophils fuse together to form foreign body giant cells in a granulomatous inflammation caused by foreign bodies,
or to form Langhan’s giant cells in tuberculosis
FALSE!
MACROPHAGES fuse together!
Which of these mediators is preformed in mast cells?
histamine
leukotriene
nitric oxide
prostaglandin
complements
histamine
Excessive granulation tissue in the skin of an equine may result in
proud flesh
The least important feature of neoplastic malignancy is:
High mitotic index
Anaplasia
Metastasis
Cellular differentiation
cellular differentiation
Empyema has the same type of exudate as:
Abscess
Tuberculosis
Granuloma
Hydromyelia
abscess
(purulent)
Healing of a deep and wide skin ulcer will most likely be by:
regeneration
replacement with fibrous tissue
replacement with fibrinous tissue
primary union
replacement with FIBROUS tissue
Some neoplasms are difficult to categorize into either carcinoma or sarcoma. The best example of such a neoplasm is:
Lymphosarcoma
Malignant hepatoma
Malignant melanoma
Carcinoma-in-situ
malignant melanoma
T/F:
Hydraencephaly is excessive accumulation of fluid in the ventricles of the brain
FALSE!
hydrocephalus is in the ventricles
On histological examination, a lesion of bovine small intestine revealed a simple granuloma which contained acid-fast bacilli.
The lesion was most likely caused by:
- streptococcus spp.*
- mycobacterium bovis*
- corynebacterium pseudotuberculosis*
- mycobacterium paratuberculosis*
mycobacterium paratuberculosis
(Johne’s disease)
Replacement of dead cells cannot occur by regeneration in tissues composed of:
labile cells
stable cells
permanent cells
stem cells
permanent cells
Wound contraction is primarily mediated by:
smooth muscle cells
macrophages
fibrin
myofibroblasts
myofibroblasts
Fat necrosis is often associated with:
acute hepatitis
a high calorie diet
acute pancreatitis
acute splenitis
acute pancreatitis
T/F:
In the sequence of leukocyte events in inflammation caused by staphylococcus aureus, the leukocytes attach to endothelium, then transmigrate through the interendothelial junctions, pierce the vascular basement membrane, and migrate along a concentration gradient of inflammatory mediator
TRUE
You were invited to St. Kitts to perform necropsy on an old cow. You observed several discrete lesions measuring between 2 and 5 cm in diameter in the lungs only. On cross section of the lesions, you heard gritty sound and observed cheese-like pale content. Bacteriology of several lesions yielded pure growth of mycobacterium bovis.
What is the MDx?
Tuberculosis (granulomatous) pneumonia
You were invited to St. Kitts to perform necropsy on an old cow. You observed several discrete lesions measuring between 2 and 5 cm in diameter in the lungs only. On cross section of the lesions, you heard gritty sound and observed cheese-like pale content. Bacteriology of several lesions yielded pure growth of mycobacterium bovis.
Histopathologically, the most predominant inflammatory cells in the lesions would be?
Macrophages, epitheloid cells, Langhan’s giant cells, and fibroblasts
You were invited to St. Kitts to perform necropsy on an old cow. You observed several discrete lesions measuring between 2 and 5 cm in diameter in the lungs only. On cross section of the lesions, you heard gritty sound and observed cheese-like pale content. Bacteriology of several lesions yielded pure growth of mycobacterium bovis.
The inflammation could be classified as?
CHRONIC
(because granulomatous)
T/F:
The presence of a disease process (type of neoplasm or abscess) at a site distant from the site of origin is known as metastasis
TRUE!
(yes, even an abscess)
Which of these infectious agents can cause
bovine cerebellar hypoplasia**?
Rabies Virus
Bovine Viral Diarrhea
Staphylococcus aureus
Bovine Papilloma Virus
bovine viral diarrhea
T/F:
A neoplasm is an inflammatory lesion
FALSE
not inflammatory
T/F:
Carcinoma-in-situ refers to a malignant neoplasm of epithelial origin that has not penetrated the basement membrane
TRUE
What type of exudates occurs commonly in parasite infestation?
Purulent
Hemorrhagic
Eosinophilic
Lymphocytic
eosinophilic
A pseudomembrane is what type of exudate?
Purulent
Fibrous
Serous
Fibrinous
fibrinous
What is the special stain for the fibrinous exudate pseudomembrane on the intestine?
PTAH
If fibrinous tissue pseudomembrane organizes, what tissue replaces it?
FIBROUS tissue
Anthrax infection
is associated with what exudative inflammatory response?
Hemorrhagic inflammation
Diphtheritic enteritis
is associated with what exudative inflammatory response?
Fibrinous inflammation
Rabies infection
is associated with what exudative inflammatory response?
Lymphocytic inflammation
Mycobacterium paratuberculosis
is associated with what exudative inflammatory response?
Granulomatous inflammation
(chronic, Johne’s DZ)
Phlegmonous pneumonia
is associated with what exudative inflammatory response?
purulent inflammation
T/F:
The major processes of inflammation include:
Increased blood flow
Lekocyte exudation
Increased vascular permeability
TRUE
Helminth parasite associated with animal neoplasia in St. Kitts dogs is:
Spirocerca
(osteosarcoma)
Exudation in ACUTE inflammation includes all of the following EXCEPT:
Serous
Fibrinous
Fibrinopurulent
Suppurative
Epitheloid
epitheloid is chronic
other chronic types of inflammation include
(**fibrous **and granulomatous)
The majority of CHRONIC inflammatory responses are dependent PRIMARILY on:
Macrophages
Blood vessels
Collagen
Macrophages and fibroblasts
Fibroplasia
Macrophages AND** fibroblasts**
The most predominant cell in non-suppurative inflammation is:
Polymorphonuclear cells
Lymphocytes
Monocytes
Macrophages
None of the above/Not a true statement
lymphocytes
Transforms into another type of cell outside blood vessels:
Polymorphonuclear cells
Lymphocytes
Monocytes
Macrophages
None of the above/Not a true statement
monocytes
The precursor of plasma cells:
Polymorphonuclear cells
Lymphocytes
Monocytes
Macrophages
None of the above/Not a true statement
lymphocytes
(b-cells, b-lymphocytes)
Polymorphonuclear cells include epitheloid cells:
Polymorphonuclear cells
Lymphocytes
Monocytes
Macrophages
None of the above/Not a true statement
none of the above
polymorphonuclear cells only include neutrophils. basophils, eosinophils, and mast cells
Epitheloid cells are mononuclear and include monocytes and macrophages, platelets, plasma cells, and lymphocytes
Most important in inflammatory leukocyte exudation:
Polymorphonuclear cells
Lymphocytes
Monocytes
Macrophages
None of the above/Not a true statement
Polymorphonuclear cells
neutrophils
Most important in formation of giant cells in some types of granulomas:
Polymorphonuclear cells
Lymphocytes
Monocytes
Macrophages
None of the above/Not a true statement
Macrophages
A condition characterized by a reduction in tissue perfusion and oxygen delivery below the levels required to meet normal demands is the definition for:
SHOCK
An ACUTE inflammatory response is dependent on:
Neutrophils
Bacteria
Blood vessels
Mediators
blood vessels
Which is the most important factor that promotes thrombosis?
Sluggish blood flow
Endothelial injury
Increased blood flow
Increased blood coagulability
Adenoma
endothelial injury
Gram negative bacteria are a major cause of which type of shock?
septic shock
The 2 basic mechanisms that can lead to development of DIC
(disseminated intravascular coagulation) include:
Massive release of tissue thromboplastin in circulation
Widespread injury to capillary endothelial cells
Thrombocytopenia and injury to aorta
Massive release of tissue thromboplastin in circulation
Widespread injury to capillary endothelial cells
