Example Test Questions Test 2

Question 1

In Congenital Bovine Porphyria

which tissues may fluoresce red under UV light?

Answer 1

teeth, bones

kidney, lungs

Question 2

T/F:

Centrifugation can be used to differentiate between

hematuria and hemoglobinuria.

In hematuria, precipitation will form at the bottom of the tube unlike hemoglobinuria

Answer 2

TRUE

Question 3

T/F:

Physiological hemorrhages occur during inflammation

Answer 3

FALSE

Question 4

If during necropsy, you see focal blood spots less than 2mm

in diameter on the mucosa of the lower jejunum,

how would you classify them?

Answer 4

petechiae

Question 5

What three reasons are associated with slow wound healing?

Answer 5

Foreign body rxn to sutures

Malnutrition

Infection

Question 6

T/F:

Epitheloid cells may coalesce to form multinucleated giant cells like Langhan’s giant cell, which is identified by the arrangement of nuclei around the periphery of the cell

Answer 6

TRUE

Question 7

Which of the following has the least capacity for regeneration?

cardiac muscle

bone

liver parenchyma

squamous epithelium

fibrous connective tissue

Answer 7

cardiac muscle

Question 8

T/F:

Patients with disseminated intravascular coagulation (DIC)

may develop both microthrombosis and hemorrhage in many tissues

Answer 8

TRUE

Question 9

Death from shock is largely due to ischemia of what 2 organs?

Answer 9

Myocardial ischemia

Cerebral ischemia

(heart and brain)

Question 10

Which are not intravascular inflammatory cells?

neutrophils and lymphocytes

epitheloid cells and macrophages

eosinophils and basophils

plasma cells and monocytes

monocytes and platelets

Answer 10

epitheloid cells and macrophages

(monocytes are circulating, macrophages are in tissue)

Question 11

Which of these is not characteristic of chronic inflammation?

macrophages

plasma cells

Langhan’s giant cells

Fibroblasts

Neutrophils

Answer 11

Neutrophils

are characteristic of acute inflammation, not chronic

Question 12

What 2 things are granulation tissue mainly composed of?

Answer 12

Angioblasts and Fibroblasts

Question 13

T/F:

Cellulitis is a diffuse suppurative lesion without a connective tissue capsule and commonly seen in subQ tissue and fascial planes of muscles

Answer 13

TRUE

Question 14

T/F:

Neutrophils fuse together to form foreign body giant cells in a granulomatous inflammation caused by foreign bodies,

or to form Langhan’s giant cells in tuberculosis

Answer 14

FALSE!

MACROPHAGES fuse together!

Question 15

Which of these mediators is preformed in mast cells?

histamine

leukotriene

nitric oxide

prostaglandin

complements

Answer 15

histamine

Question 16

Excessive granulation tissue in the skin of an equine may result in

Answer 16

proud flesh

Question 17

The least important feature of neoplastic malignancy is:

High mitotic index

Anaplasia

Metastasis

Cellular differentiation

Answer 17

cellular differentiation

Question 18

Empyema has the same type of exudate as:

Abscess

Tuberculosis

Granuloma

Hydromyelia

Answer 18

abscess

(purulent)

Question 19

Healing of a deep and wide skin ulcer will most likely be by:

regeneration

replacement with fibrous tissue

replacement with fibrinous tissue

primary union

Answer 19

replacement with FIBROUS tissue

Question 20

Some neoplasms are difficult to categorize into either carcinoma or sarcoma. The best example of such a neoplasm is:

Lymphosarcoma

Malignant hepatoma

Malignant melanoma

Carcinoma-in-situ

Answer 20

malignant melanoma

Question 21

T/F:

Hydraencephaly is excessive accumulation of fluid in the ventricles of the brain

Answer 21

FALSE!

hydrocephalus is in the ventricles

Question 22

On histological examination, a lesion of bovine small intestine revealed a simple granuloma which contained acid-fast bacilli.

The lesion was most likely caused by:

• streptococcus spp.*
• mycobacterium bovis*
• corynebacterium pseudotuberculosis*
• mycobacterium paratuberculosis*

Answer 22

mycobacterium paratuberculosis

(Johne’s disease)

Question 23

Replacement of dead cells cannot occur by regeneration in tissues composed of:

labile cells

stable cells

permanent cells

stem cells

Answer 23

permanent cells

Question 24

Wound contraction is primarily mediated by:

smooth muscle cells

macrophages

fibrin

myofibroblasts

Answer 24

myofibroblasts

Question 25

Fat necrosis is often associated with: acute hepatitis a high calorie diet acute pancreatitis acute splenitis

Answer 25

**acute pancreatitis**

Question 26

T/F: In the sequence of leukocyte events in inflammation caused by *staphylococcus aureus*, the leukocytes attach to endothelium, then transmigrate through the interendothelial junctions, pierce the vascular basement membrane, and migrate along a concentration gradient of inflammatory mediator

Answer 26

TRUE

Question 27

You were invited to St. Kitts to perform necropsy on an old cow. You observed several discrete lesions measuring between 2 and 5 cm in diameter in the lungs only. On cross section of the lesions, you heard gritty sound and observed cheese-like pale content. Bacteriology of several lesions yielded pure growth of *mycobacterium bovis*. What is the **MDx?**

Answer 27

Tuberculosis (granulomatous) pneumonia

Question 28

You were invited to St. Kitts to perform necropsy on an old cow. You observed several discrete lesions measuring between 2 and 5 cm in diameter in the lungs only. On cross section of the lesions, you heard gritty sound and observed cheese-like pale content. Bacteriology of several lesions yielded pure growth of mycobacterium bovis​. ## Footnote **Histopathologically, the most predominant inflammatory cells in the lesions would be?**

Answer 28

**Macrophages, epitheloid cells, Langhan's giant cells, and fibroblasts**

Question 29

You were invited to St. Kitts to perform necropsy on an old cow. You observed several discrete lesions measuring between 2 and 5 cm in diameter in the lungs only. On cross section of the lesions, you heard gritty sound and observed cheese-like pale content. Bacteriology of several lesions yielded pure growth of mycobacterium bovis​. ## Footnote **The inflammation could be classified as?**

Answer 29

**CHRONIC** | (because granulomatous)

Question 30

T/F: The presence of a disease process (type of neoplasm or abscess) at a site distant from the site of origin is known as metastasis

Answer 30

TRUE! | (yes, even an abscess)

Question 31

Which of these infectious agents can cause bovine *cerebellar hypoplasia**?* Rabies Virus Bovine Viral Diarrhea *Staphylococcus aureus* Bovine Papilloma Virus

Answer 31

**bovine viral diarrhea**

Question 32

T/F: A neoplasm is an inflammatory lesion

Answer 32

FALSE not inflammatory

Question 33

T/F: Carcinoma-in-situ refers to a malignant neoplasm of epithelial origin that has not penetrated the basement membrane

Answer 33

TRUE

Question 34

What type of exudates occurs commonly in parasite infestation? Purulent Hemorrhagic Eosinophilic Lymphocytic

Answer 34

**eosinophilic**

Question 35

A pseudomembrane is what type of exudate? Purulent Fibrous Serous Fibrinous

Answer 35

**fibrinous**

Question 36

What is the special stain for the fibrinous exudate pseudomembrane on the intestine?

Answer 36

PTAH

Question 37

If fibrinous tissue pseudomembrane organizes, what tissue replaces it?

Answer 37

**FIBROUS** tissue

Question 38

Anthrax infection is associated with what exudative inflammatory response?

Answer 38

Hemorrhagic inflammation

Question 39

Diphtheritic enteritis is associated with what exudative inflammatory response?

Answer 39

Fibrinous inflammation

Question 40

Rabies infection is associated with what exudative inflammatory response?

Answer 40

Lymphocytic inflammation

Question 41

*Mycobacterium paratuberculosis* is associated with what exudative inflammatory response?

Answer 41

Granulomatous inflammation | (chronic, Johne's DZ)

Question 42

Phlegmonous pneumonia is associated with what exudative inflammatory response?

Answer 42

purulent inflammation

Question 43

T/F: The major processes of inflammation include: Increased blood flow Lekocyte exudation Increased vascular permeability

Answer 43

TRUE

Question 44

Helminth parasite associated with animal neoplasia in St. Kitts dogs is:

Answer 44

*Spirocerca* | (osteosarcoma)

Question 45

Exudation in ACUTE inflammation includes all of the following EXCEPT: Serous Fibrinous Fibrinopurulent Suppurative Epitheloid

Answer 45

**epitheloid** is chronic other chronic types of inflammation include (**fibrous **and **granulomatous**)

Question 46

The majority of CHRONIC inflammatory responses are dependent PRIMARILY on: Macrophages Blood vessels Collagen Macrophages and fibroblasts Fibroplasia

Answer 46

**Macrophages** AND** fibroblasts**

Question 47

The most predominant cell in non-suppurative inflammation is: Polymorphonuclear cells Lymphocytes Monocytes Macrophages None of the above/Not a true statement

Answer 47

lymphocytes

Question 48

**Transforms into another type of cell outside blood vessels:** Polymorphonuclear cells Lymphocytes Monocytes Macrophages None of the above/Not a true statement

Answer 48

**monocytes**

Question 49

**The precursor of plasma cells:** Polymorphonuclear cells Lymphocytes Monocytes Macrophages None of the above/Not a true statement

Answer 49

**lymphocytes** **(b-cells, b-lymphocytes)**

Question 50

Polymorphonuclear cells include epitheloid cells: Polymorphonuclear cells Lymphocytes Monocytes Macrophages None of the above/Not a true statement

Answer 50

**none of the above** *polymorphonuclear cells only include neutrophils. basophils, eosinophils, and mast cells* Epitheloid cells are mononuclear and include monocytes and macrophages, platelets, plasma cells, and lymphocytes

Question 51

**Most important in inflammatory leukocyte exudation:** Polymorphonuclear cells Lymphocytes Monocytes Macrophages None of the above/Not a true statement

Answer 51

Polymorphonuclear cells ## Footnote **neutrophils**

Question 52

**Most important in formation of giant cells in some types of granulomas:** Polymorphonuclear cells Lymphocytes Monocytes Macrophages None of the above/Not a true statement

Answer 52

**Macrophages**

Question 53

A condition characterized by a reduction in tissue perfusion and oxygen delivery below the levels required to meet normal demands is the definition for:

Answer 53

**SHOCK**

Question 54

An ACUTE inflammatory response is dependent on: Neutrophils Bacteria Blood vessels Mediators

Answer 54

**blood vessels**

Question 55

Which is the most important factor that promotes thrombosis? Sluggish blood flow Endothelial injury Increased blood flow Increased blood coagulability Adenoma

Answer 55

**endothelial injury**

Question 56

Gram negative bacteria are a major cause of which type of shock?

Answer 56

**septic shock**

Question 57

The 2 basic mechanisms that can lead to development of DIC (disseminated intravascular coagulation) include: Massive release of tissue thromboplastin in circulation Widespread injury to capillary endothelial cells Thrombocytopenia and injury to aorta

Answer 57

**Massive release of tissue thromboplastin in circulation** **Widespread injury to capillary endothelial cells**