PPQ3 Flashcards
Atropine is used for
Bradycardia caused by opioids; Reflex-bradycardia caused by alpha2-agonists (high BP);
AV-blocks & SA-blocks
ACP effects
Calming; Vasodilator; Depression of thermoregulation; Decreases BP; Antihistaminic;
Depression of platelet function
diazepam and midazolam
For old animals with poor general circulation; Decreases anxiety; Relaxes muscles;
High dose can caused respiratory depression
alpha 2 agonists
Sedative effect; Emetic; Antagonisable by atipamezole; Detomidine; Medetomidine;
Dexmedetomidine; Xylazine
medetomidine and xylazine
Using a general dose - phases of sedation, induction & maintenance cannot be
separated; Not recommended for old, cardiac & diabetic patients; Cause circulatory &
respiratory depression
opioid drugs
Major analgesics; Side effects are bradycardia & respiratory depression; Can be
antagonised by naloxone; Morphine; Fentanyl; Buprenorphine; Butorphanol
(Torbugesic); They all have differing levels of efficacy
opioid receptors
μ (Mu); k (Kappa); δ (Delta)
fentanyl
full agonist opioid drug; 15-30 minute duration of effect; may be redosed
morphine
Full agonist opioid drug; 4-6 hours duration of effect; Use high dose IV in mastocytoma
patients; Must not be redosed!
full opioid agonists
morphine; fentanyl
short duration of action
fentanyl
Partial μ-agonist
buprenorphine
Partial μ-antagonist & k-agonist
butorphanol
Weak μ-agonist
tramadol
propofol
Can be used in almost all patient groups; Short duration of action; Can be redosed;
High dose and rapid application lead to respiratory depression
application of propofol
slowly; IV; to effect
ketamine
Moderate analgesic effect; Benzodiazepines may help avoid catalepsy (muscle rigidity);
Eyes remain open, therefore the cornea may desiccate
safe inhalant anaesthetics
isoflurane, sevoflurane, desflurane
inhalant anaesthetics
1 MAC causes muscle relaxation in 50% of cases; 2 MAC causes muscle relation in
100% of cases; Short induction and recovery; Hypnotic; Muscle relaxant; No analgesic
effect
local anaesthetic
Blocks nerve cells; Types - Terminal, conductive, paravertebral, epidural & spinal;
Possible side effects – Cardiovascular & CNS signs, cell toxicity
Pancuronium; Atracurium; Vecuronium; Rocuronium
Central muscle relaxants; Peripheral depolarising muscle relaxants; Local anaesthetics
pain
Complex, multidimensional negative experience; No linear correlation between degree
of pathological changes and intensity of pain; Simultaneous nociceptive effects add up;
Function – Physiological or pathological; Origin – Organic or psychogenic; Duration –
Acute or chronic
pathological pain
Hyperalgesia: Mild noxious stimuli resulting in intense pain sensation; Allodynia: No
pain provocation, but pain sensation occurs; Analgesia can be combined; Pain impulse
may be inhibited by pain killers
ascending pathway of nociception
Transduction → Transmission → Modulation → Projection → Perception
modern concepts of pain management
Pre-emptive (prophylactic) analgesia; Multimodal analgesia; No gap should appear
intraoperative analgesic effect
Ketamine CRI; Lidocaine + fentanyl CRI; Local anaesthetic + opioids
purpose of anaesthesia machines
Administration of appropriate oxygen flow; Administration of appropriate inhalant
concentration; Elimination of exhales CO2
mixing part of the anaesthesia machine
gas source; flow meter; vaporiser
breathing circuit of the anaesthesia machine
‘Y’piece; resevoir bag; CO2 absorbent canister
oxygen by-pass
emergency option; concentration of inhalational anaesthetic in the circuit can be quickly reduced; pure3 O2 can directly enter the circuit
optimal breathing tubes are
ribbed; short and wide
optimal size of reservoir bag
5 times the respiratory volume
the absorbent cannister is part of the
open system; semi open system; semi closed system
CO2 absorption
The absorbent canister contains absorbing soda; The absorbing soda granules have a
rough surface; Exhaustion of the soda is indicated by discoloration
pop-off valve (adjustable pressure limiting value)
Prevents excessive pressure in the circuit & lungs; Is open during spontaneous
breathing; Is set to 20 cmH2O during manual or mechanical ventilation
advantages of semi open narcosis system
Low-resistance; Small mechanical dead space; Anaesthetic concentration can be
quickly modified
advantages of a closed narcosis systems
Low gas consumption; Low inhalational anaesthetic consumption; Cheap
narcosis system types
Semi-open system; Semi-closed circuit; Closed circuit
indications for mechanical ventilation
Severe hypoxia; Severe hypercapnia; Excessive work of breathing; Open thorax;
Hypoventilation caused by hypothermia; Neuromuscular blockade
IPPV
Airway pressure is higher than atmospheric pressure during inspiration; Airway
pressure falls to atmospheric pressure during passive expiration; Cannot be used in
large dogs