pp clues obgyn ped Flashcards
What does the Seminal Vesicle give to sperm?
Food (fructose) and clothes (semen)
What do the Bulbourethral = Cowper’s glands secrete?
Bicarbonate (neutralize lactobacilli)
What does the Prostate secrete?
“The prostate HAZ it”
Hyaluronidase Acid phosphatase
What is the Capacitation reaction?
Zn used to peel semen off
What is the Acrosomal reaction?
Sperm release enzymes to eat corona radiata
What is the Crystalization reaction?
Wall formed after 1 sperm enters (to prevent polyspermy) the egg
Where does Testosterone come from?
Adrenal gland and testicles
Where does DHT come from?
Testicles (at puberty)
What is a Pseudohermaphrodite?
External genitalia problem; does not match genotype
What is a True Hermaphrodite?
internal genitalia problem => has both sexes’ genitalia
What is a Female Hermaphrodite?
Impossible b/c the default is female
What is a Female Pseudohermaphrodite?
XX with low 21-OHase
=> high testosterone
What is a Male Hermaphrodite?
XY with no MIF
What is a Male Pseudohermaphrodite?
XY that has low 17-OHase => low testosterone
What is Hirsuitism?
Hairy
Hi testoterone
What is Virilization?
female child with male sexual charcateristic
What is Testicular Feminization = Androgen Insensitivity
Bad DHT receptor w/ blind pouch vagina
What is McCune-Albright?
Precocious sexual development, polyostotic fibrous dysplasia “whorls of CT”, “Coast of Maine” pigmented skin macules
What is Cryptochordism?
Testes never descended => sterility after 15mo, seminomas
Which stage of the menstrual cycle has the highest estrogen levels?
Follicular stage (has
proliferative endothelium)
What stage of the menstrual cycle has the highest temperature?
Ovulatory stage
What stage of the menstrual cycle has the highest progesterone levels?
Luteal stage (has secretory endothelium)
What form of estrogen is highest at menopause?
E1: Estrone (made by fat)
What form of estrogen is highest in middle-age females?
E2: Estradiol (made by ovaries)
What form of estrogen is highest at pregnancy?
E3: Estriol (made by placenta)
What states have increased estrogen?
Pregnancy, liver failure, p450 inhibition, obesity
What is Adenomyosis?
Growth of endometrium myometrium, enlarged “boggy” uterus w/ cystic areas
What does DES taken by Mom cause in her daughter?
Adenomyosis–>menorrhagia
->Clear Cell CA of the vagina
-> Recurrent abortions from cervical
incompetence
What is Kallman’s syndrome?
No GnRH, anosmia (can’t smell)
What is Polycystic Ovarian Syndrome?
^Cysts: no ovulation-> progesterone
(^ endometrial CA) ->can’t inhibit LH, obese, hairy, acne
What is Savage’s syndrome?
Ovarian resistance to FSH/LH
What is Turner’s syndrome (XO)?
High FSH, low estrodiol( E2), ovarian dysgenesis
What does the Progesterone challenge test tell you?
Bleeds => she has estrogen
Not bleed => she has no E2 or ovaries
^FSH->Ovary problem
low FSH->pituitary problem
What is Sheehan syndrome?
Post-partum hemorrhage->pituitary, hyperplasia infarcts ->no lactation
What is Asherman’s syndrome?
Previous D&C ->uterine scars
What is Oligomenorrhea?
Too few periods
What is Polymenorrhea?
Too many periods
mcc of post- coital vaginal bleeding?
Cervical cancer
What is the most common cause of post- coital vaginal bleeding in pregnant women?
Placenta previa
mcc of vaginal bleeding in post-
menopause women?
Endometrial cancer
What is Dysmenorrhea?
mcc of teenage seeing a doctor
PG-F causes painful menstrual cramps (teenagers miss school/work)
What is Endometriosis?
Painful cyclical heavy menstrual bleeding
=> “powder burns, chocolate cysts” due to ectopic endometrial tissue
What is Kleine regnung?
Scant bleeding at ovulation
What is Menorrhagia?
Heavy menstrual bleeding
What is Fibroids = Leiomyoma?
Benign uterus SM tumor
-> Submucosal type => bleeding
-> Subserosal type => pain
What is Metrorrhagia?
Bleeding or spotting in between periods
What is Mittelschmerz?
Pain at ovulation
What causes Syphilis?
Treponema pallidum (spirochete)
What is Herpes?
ds DNA virus
What is HPV?
ds DNA virus
What is Chlamydia?
Obligate intracellular parasite
What causes Gonorrhea?
Gram – diplococcus
What causes Chancroid?
H. ducreyi
What causes
Lymphogranuloma Venereum?
Chlamydia trachomatis
What causes Granuloma Inguinale?
C. granulomatosis
What causes Epididymitis?
Chlamydia or GC
What is Condyloma Lata?
Flat fleshy warts, ulcerate, 2° Syphilis
What is Condyloma Accuminata?
Verrucous “cauliflower” warts, koilocytes, HPV 6,11
How does Herpes present?
1°: Painful grouped vesicles on red base 2°: Painful solitary lesion
How does Syphilis present?
1°: Painless chancre (1-6 wks)
2°: Rash, condyloma lata (6 wks)
3°: Neuro, cardio, bone (6yrs)
How does Chancroid present?
Painful w/ necrotic center, Gram –rod, “school of fish” pattern
How does Lymphogranuloma Venereum present?
Painless ulcers→abscessed nodes→
genital elephantiasis
How does Granuloma Inguinale present?
Spreading ulcer, Donovan
bodies, granulation test
How does Chlamydia present?
in females
Cervicitis (yellow pus), conjunctivitis, PID
How does Gonorrhea present?
purulent urethral discharge
(yellow-green)
dysuria
arthritis,
cervicitis
PID
Palmer rash
purulent yellow malodor discharge
perihepatitis
What is Epididymitis?
Unilateral scrotal pain decreased by support
What causes Congenital blindness?
CMV
HHV-5-owl eye
ganciclovir
What causes Neonatal blindness?
Chlamydia
azithromycin
What is Lichen simplex chronicus?
Raised white lesions, chronic scratching in vulva
What is Lichen sclerosis?
Paper-like vulva, itching, cancer risk
What is Hidradenoma?
Sweat gland cysts
T(ToRCHes)
What causes non-bacterial fetal infections?
T (TORCHes)
“TORCHeS”
=>Toxoplasma: multiple ring-enhancing lesions,
cat
urine,
parietal lobe Others
R
ToRCHeS
=>Rubella: cataracts,
hearing loss,
persistant PDA,
meningoencephalitis,
pneumonia,
“blueberry muffin” rash
C
ToRCHeS
DS dna virus
=>CMV: spastic diplegia of legs,
hepatosplenomegaly,
blindness,
central calcifications
H
ToRCHeS
=>HSV-2: temporal lobe hemorrhagic
encephalitis,
S
ToRCHeS
=>Syphilis: Rhagade’s (lip fissure),
saber
shin legs,
Hutchison’s razor teeth,
mulberry molars,
saddle nose
What is Paget’s disease of the breast?
Rash and ulcer around nipple, breast cancer
What is Lobular carcinoma?
Cells line up single file, contralateral primary
What is a Comedocarcinoma?
Multiple focal areas of necrosis, “blackheads”
What is Inflammatory carcinoma?
Infiltrates lymphatics, pulls on Cooper’s ligaments,“peau d’orange”
What is Cystosarcoma phylloides?
“Exploding mushroom”, firm, rubbery, moveable,good prognosis
What is Intraductal papilloma?
Nipple bleeding
What is Ductal carcinoma?
Worst prognosis breast cancer
What is Sarcoma Botyroides?
Vagina cancer, ball of grapes appearance
What is a Sister Mary Joseph Nodule?
Ovarian CA spread to umbilicus
What is Meig’s syndrome?
Pleural effusion, ovarian fibroma, ascites
What are the side effects of estrogen?
Weight gain, breast tenderness, nausea,
relaxation
What are the side effects of progesterone?
Acne, depression, HTN
increase apetite, aggressive, polycythemia
Why do pregnant women get anemia?
Dilutional effect; RBC rises 30% but volume rises 50%
What are the degrees of vaginal lacerations?
1st Degree: Skin
2nd Degree: Muscle
3rd Degree: Anus
4th Degree: Rectum
What is Vernix?
Cheesy baby skin
What is Meconium?
Green baby poop
What is Lochia?
Endometrial slough
What is normal blood loss
during a vaginal delivery?
500mL
What is normal blood loss during a C- section?
1L
How do you treat A1 Gestational DM?
Diet
How do you treat A2 Gestational DM?
Insulin
What are identical twins?
Egg split into perfect halves “monochorionic”
What are fraternal twins?
Multiple eggs fertilized by different sperm
What is Ovarian
Hyperstimulation Syndrome?
Weight gain and enlarged ovaries after clomiphene use
Who makes the Trophoblast?
Baby
Who makes the Cytotrophoblast?
Mom => GnRH, CRH, TRH, Inhibin