micro Drill sheet part 2 Flashcards
Periods of rapid growth
Birth - 2months
4 - 7 years
Puberty
Pregnancy
healing
cancer
Only immune deficiency with Low Calcium
DiGeorge’s Syndrome
Bugs with IgA Protease
S. Pneumonia
H. Influenza
Neisseria (are resistant
to IgA)
Secretions of Mast Cells
Histamine
Slow Reacting Substance
of Anaphylaxis
Eosinophil Chemotactic
Factor of Anaphylaxis
Secretions of Eosinophil
Histaminase
Arylsulfatase
Heparin
Actions of E. coli
Secrete Vitamin K
Secrete Biotin
Secrete Folate
Secrete Pantothenic acid
Aid in absorption of B12
Heart Block
Increased body temperature with a normal heart rate.
HR should increase by 10bpm per 1 degree increase in temperature
Macrophages
Release MHC II
TH1 Secrete
IL-2
IF-
TH2 Secrete
IL-4
IL-5
IL-6
IL-10
T-Cytotoxic Cells
CD-8 positive
CD-4 negative
Recognize MHC I
Also have markers
CD-2 and CD-3
T-Helper Cells
CD-4 positive
CD-8 negative
Recognize MHC II
Also have marker CD-2
and CD-3
Elevated Cholesterol
Xanthomas on extensor surfaces
^ Risk for CAD
Elevated Triglycerides
Xanthelasmas on eyelids and face
^ risk of Pancreatitis
4 Causes of Severe
Abdominal Pain
Pancreatitis (EtOH)
Kidney Stones (bloody urine)
AAA (ripping, tearing pain)
Ischemic Bowel (bloody diarrhea)
5 Causes of SIADH
(SIADH)
Small Cell Carcinoma
^ intracranial pressure
A Pain
Drugs
Hypoxia
Neural Crest Cells
(POT CLAMPSS)
Parafollicular cells
Odontoblast
Tracheal cartilage
Chromaffin cells
Laryngeal cartilage
All Ganglion cells
Melanocytes
Pseudounipolar cells
Spiral membrane
Schwann cells
Ions and the EKG
P-wave = Ca++
QRS complex = Na+
S-T Interval = Ca++
T-wave = K+
U-wave = Na+
Maximum Sinus Rate
220 - age in years
Tri-Nucleotide Repeats
Huntington’s
Fragile X
Myotonic dystrophy
Spinal/bulbar muscular
atrophy (rare)
Low volume states with acidosis (not alkalosis)
RTA
Diarrhea
MCC Croup & Bronchiolitis
Parainfluenza
RSV (ER this is #1)
Adenovirus
Influenza
4 D’s of Pellagra
Dermatitis
Diarrhea
Dementia
Death
Types of Kidney Stones
Calcium oxalate
80%
Struvite
Uric Acid
Cysteine
Oxalate
Types of Kidney Stones
Calcium oxalate
80%
Struvite
Uric Acid
Cysteine
Oxalate
Pseudogout
Ca++ pyrophosphate
Birefringent crystals
Rhomboid crystals
MC older patients
Seen equally in both genders
TX = Colchicine
Pseudogout
Ca++ pyrophosphate
Birefringent crystals
Rhomboid crystals
MC older patients
Seen equally in both genders
TX = Colchicine
MC Non-cyanotic Congenital Heart Dz
VSD
ASD
PDA
Coarctation of aorta
Enzymes NEVER seen in Glycolysis
Pyruvate carboxylase PEP carboxykinase
Fructose-1,6-phosphatase Glucose-6-phosphatase
Enzymes NEVER seen in Glycolysis
Pyruvate carboxylase
PEP carboxykinase
Fructose-1,6-phosphatase
Glucose-6-phosphatase
Enzymes ONLY seen in Glycolysis
Hexokinase
Phosphofructokinase-1
Pyruvate kinase
Acid Fast Organisms
Mycoplasma
Nocardia (partially gr+)
Cryptosporidium (Partially
protozoa)
Causes of Microsteatosis
Acetaminophen
Reye Syndrome
Pregnancy
Causes of Macrosteatosis
Alcohol
Bacteria with Elastase
Staph. aureus
Pseudomonas
Bacteria with toxins that inhibit EF-2
Pseudomonas
Diphtheria
Phage Mediated Toxins
(Oh BED)
“O” antigen (Salmonella)
Botulinum
Erythrogenic toxin
Diphtheria
Segmented Viruses
(I sprayed ORTHO on BUNYA at the ARENA down in REO to kill SEGMENTED viruses)
Orthovirdiae
Bunyavirdiae
Arenavirdiae
Reovirdiae
Functions of Adhesion Molecules
Lymphocyte homing
Inflammation
Cell-cell interaction
Functions of Adhesion Molecules
Lymphocyte homing
Inflammation
Cell-cell interaction
Esophageal/Gastric CA Risk Factors
Smoking
Alcohol
Nitrates
Japanese
Bladder CA Risk Factors
Smoking
Aniline dyes
Benzene
Aflatoxin
Cyclophosphamide
Schistosomiasis
Von Hippel-Lindau
Tuberous Sclerosis
Structures with No Known Function
Epithalamus
Palmaris longus
Pancreatic Polypeptide
Progressing to RPGN
Goodpasture’s (#1)
Diabetes Mellitus
Hypertension
Wegener’s
Causes of Papillary Necrosis
Vasculitis
AIDS
Gram Positive Spore Formers
Bacillus anthracis
Clostridium perfrigens
Clostridium tetani
Used for Cold Agglutinin Testing
Strep. salivarius
Drugs that Cause Disulfram Reaction (CLAM)
Chlorpropamide
Lactams
Antabuse
Metronidazole
sulfa
3 Toxins of Bacillus
Lethal factor
Protective factor
Edema factor
Beta Blockers
beta 1 Selective: A-M (except C & L)
Nonselective: N-Z, C, L
Fanconi Syndrome
Defect in proximal tubule
Can’t reabsorb
Low energy state
Can be caused by old tetracycline
Glutaminase
In collecting duct
Absorbs ammonia in the liver
Cause of hepato-renal syndrome
3 Anatomical Narrowings of Ureter
Hilum
Pelvic Brim
Entrance of bladder
Odd MCC of Death
SLE, endometrial and cervical cancer
renal failure
Methotrexate Uses
DX Fragile X
TX Molar Pregnancy
TX Fast growing CA
TX Steroid resistant disease
Group D Streptococcus
Viridans
green pigment, SBE
Mutans
Cavities
Sanguis
Salivaris
Bovis
Nephritic Syndrome
Hypertension
Hematuria
RBC casts
Nephrotic Syndrome
Edema
Hyperlipidemia
Hypercholesterolemia Hypercoagulability
^ serum albumin
^urine albumin
MCC of Airway Infection
(Sinusitis, otitis, bronchitis, pneumonia)
1 S. pneumonia
#2 H. influenza
#3 N. meningitides
Gastroenteritis within 8 hours of eating
(Pre-formed toxin)
S. aureus (potato salads)
C. perfringens (holidayturkey/ham)
B. cereus (fried rice)
Citrobacter
Cause of multiple cerebral abscesses in newborns
MCC of UTI
1 E. coli
#2 Proteus
#3 Klebsiella
Most Frequent in Females 5-10 yrs and 18-24 yrs
S. saprophyticus b/c they stick things inside themselves
S. aureus
MCC of osteomyelitis MCC of infection in
burn patients
MCC of Newborn Meningitis
Group B Strep
E. coli
Listeria
Bacteria Associated with Colon Cancer
C. melanogosepticus
S. bovis
Gram that are strict anaerobes
H. flu
Neisseria
Pre-renal Failure
Serum BUN > 20
Serum Cr > 40
Fractional Na exc. < 1%
Renal Failure
Serum BUN
10 to15
Serum Cr < 20
Fractional Na exc. > 2%
Extravasation
Pavementing
Margination
Diapedesis
Migration
If Cell Mediated is defective - TX for
Viral
Fungal
Mycobacterium Protozoa
Parasite
Neoplasm
Herpes Viruses
HHV1 - oral
HHV 2 - genital
HHV3 - VZV
HHV4 - EBV
HHV5 - CMV
HHV 6 - Roseola
HHV 7 - Pityriasis rosea
HHV 8 - Kaposi’s
Disease Picked up During Delivery
Group B strep
S. pneumonia
Herpes
N. gonorrhea
Chlamydia
TORCHHeS
Toxoplasma
parvOvirus B19
Rubella
CMV
Herpes simplex
HIV
Syphilis
Neonatal Toxoplasma
Chorioretinitis
Hydrocephalus
Intracran calcifications
Neonatal PVB19
Hydrops fetalis
Neonatal Rubella
PDA
Cataracts
Deafness
Blueberry muffin rash
Neonatal CMV
Unilat. Hearing loss Seizures
Petechiae
Neonatal Herpes
Temp encephalitis Vesicles
Neonatal HIV
Recurrent infections Chronic diarrhea
Neonatal Syphilis
Saddle nose
Saber shins
Hydrops fetalis
Notched teeth
Short maxilla
Most cancer mortality in male
- Lung
- Prostate
- Colon
Male Cancers
Most prevalent
- Prostate
- Lung
- Colon
Female Cancers
Most prevalent
- Breast
- Lung
- Colon
Most mortality
- Lung
- Breast
- Colon
Gynecologic Cancers
Most prevalent
- Endometrial
- Ovarian
- Cervical
Most mortality
- Ovarian
- Endometrial
- Cervical
Most mortality
- Ovarian
- Endometrial
- Cervical
Cephalosporins that block Vitamin K
Cefotetan
Cefamandole
Cefoperazone
Moxalactam
Common bile duct stone
Pancreatitis
Alkaline phosphatase
High white count
TX for Gout. Most effective
Colchicine
1st line - Indomethacin
3rd line - Steroid (joint)
TX for Neuropathy
Amitriptyline
Gabapentin (heart dz)
Carbamazepine (shooting
pain)