fun guy Flashcards
2 things fungi loves the most
sugar
warm and moist
not that warm and moist u thinking off 😉😂
unique fungi lipid in cell membrane
ergosterol
to prevent fungi keep area
cool and dry
antifungals
physiology of antifung binding to egosterol
binds ergo–>poke holes–>K out–>Na in–>cl follows–cell dies
hyper K
think membrane physio
best system antifug
amphotericin B/Nystatin
gynecomastia
binds ergosterol
best antifung fo toe nail
Terbinafine
inhibit ergosterol synthesis
best antifung multiple toe nail
efinaconazole
best for diabetic toe fung
attack fung DNA
flucytosine
Inhibit ergosterol synthesis
best CNS penetration
fluconazole
cryptococcus infection
inhibit microtubules
induce P450
griseofulvin
Best cornea penetration
attacks rapidly dividing cells
blocks P450 the most
Ketoconazole
non systemic spread by sharing hat
piedra
detect with woodslamp
microsporum
Tinea=skin
Tinea Capitus
treat with
dundrough
griseofulvin and sellinium
attack pigmented skin, “upside-down christmas tree”
follows sweat pattern
Tinea versicolor