Polyoma And Flashcards
E7 binds to?
P105rb
E6 binds to?
P53
What is infected w warts?
Squamous epithelium
What happens when mucous membranes are infected
Genital
Oral
Conjuctival papilloma
Char of HPV infections
Koilocytes
Important for control and resolution of hpv infectns
Innate
CMI
High risk hpv types
16
18
Oncogenes of high risk hpv
E5-7
Site of immunogically privileged
Terminally differentiated cell (dead cell)
T or f? Hpv can be transmitted by fomites
True
hpv is acquired thru
Vertical transmission
Sex
Direct
VSD
T or f? Old aged adults are prone to laryngeal papilloma
False, middle
All mucosal syndromes have what type except CIN
6,11
Common wart types
2,4
All other types found in what skin wart?
Epidermodysplasia verruciformis
EV
Flat wart types?
3,10
Warts can be confirmed histo what are seen?
Hyperplasia of pickle cells
Xs keratin
T or f? culture relevant in HPV
False
Tx that stimulates innate and inflammatory responses
Imiquimod
Interferon
Tx to treat hpv infected cells
Cidofovir
In hpv pap smeArs can replace vaccines tor f
F
Less prevalent polyoma
Bi
Wu
Merkel cell
Prototype of polyoma
Sv40
Encoded for non structural proteins of polyoma
Early
Late region codes for?
Capsid proteins-vp1,2,3
Noncoding region contains
OriC
Control sequence for early and late