Polyoma And Flashcards

0
Q

E7 binds to?

A

P105rb

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1
Q

E6 binds to?

A

P53

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2
Q

What is infected w warts?

A

Squamous epithelium

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3
Q

What happens when mucous membranes are infected

A

Genital
Oral
Conjuctival papilloma

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4
Q

Char of HPV infections

A

Koilocytes

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5
Q

Important for control and resolution of hpv infectns

A

Innate

CMI

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6
Q

High risk hpv types

A

16

18

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7
Q

Oncogenes of high risk hpv

A

E5-7

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8
Q

Site of immunogically privileged

A

Terminally differentiated cell (dead cell)

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9
Q

T or f? Hpv can be transmitted by fomites

A

True

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10
Q

hpv is acquired thru

A

Vertical transmission
Sex
Direct
VSD

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11
Q

T or f? Old aged adults are prone to laryngeal papilloma

A

False, middle

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12
Q

All mucosal syndromes have what type except CIN

A

6,11

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13
Q

Common wart types

A

2,4

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14
Q

All other types found in what skin wart?

A

Epidermodysplasia verruciformis

EV

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15
Q

Flat wart types?

A

3,10

16
Q

Warts can be confirmed histo what are seen?

A

Hyperplasia of pickle cells

Xs keratin

17
Q

T or f? culture relevant in HPV

A

False

18
Q

Tx that stimulates innate and inflammatory responses

A

Imiquimod

Interferon

19
Q

Tx to treat hpv infected cells

A

Cidofovir

20
Q

In hpv pap smeArs can replace vaccines tor f

A

F

21
Q

Less prevalent polyoma

A

Bi
Wu
Merkel cell

22
Q

Prototype of polyoma

A

Sv40

23
Q

Encoded for non structural proteins of polyoma

A

Early

24
Q

Late region codes for?

A

Capsid proteins-vp1,2,3

25
Q

Noncoding region contains

A

OriC

Control sequence for early and late