4B-3 Flashcards
0
Q
Only Char of prions same with virus
A
FP
Filterable infectious
Presence of proteins
1
Q
Spongiform encephalopathy
A
Prions
2
Q
Prototype
A
Scrapie
3
Q
Difference of prpsc and prpc
A
Sc:
Multimeric
Location-cytoplasmic
4
Q
How do they cause dse?
A
Template mediated protein refolding
5
Q
Prpc is encoded in what chromosome
A
20
6
Q
Strains of prpsc continues how?
A
Mutate prpc
Self folding of prpsc
7
Q
Determines severity of cjd
A
Cdon 129
8
Q
Appearance of vacuolated neurons, loss of fcn, no immune
A
Spongiform enceph
9
Q
Protein marker seen in csf
A
14-3-3
10
Q
Incubation perood?
A
Long, 30 yrs
11
Q
Transmission?
A
Fict Food Injection Contact thru medical dvce Transplantation
12
Q
Ibheritable dseases
A
CJD
FFI
GSS
13
Q
Means shivering dse
A
Kuru
14
Q
Dse w sporadic occurence
A
Gss
Cjd
