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Micro > Picorna > Flashcards

Picorna Flashcards

0
Q

6 genera (ERHPAC)

A 
Enterovirus
Rhinovirus
Hepatovirus
Parecho
Aphtho
Cardio
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1
Q

One of the first viruses to be identified

A

Foot and mouse disease virus

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2
Q

4 major groups of human pathogens

A

Entero
Rhino
Hepatovirus
Parecho

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3
Q

Most serious disease vy any enterovirus

A

Poliomyelitis

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4
Q

Genus of humen entero

A 
Poliovirus (1-3)
Cox A 1-24
Cox B 1-6
Echo 1-33
Entero 68-78
Entero 79- 101
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5
Q

Most rhinovirus can br recovered only in human cells at what temp?

A

33C

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6
Q

Originally classified as enterovirus 72

A

Hep A

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7
Q

Previously echo 22 and 23

A

Parechovirus

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8
Q

Encephalomypcarditis of rodents

A

Cardiovirus

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9
Q

Foot and mouth disease of cattle

A

Aptho

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10
Q

Contains genome linked protein

A

VPg

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11
Q

The 5’ longer end has a cloberleaf structure called?

A

IRES

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12
Q

Surface capsid proteins

A

VP1 and VP

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13
Q

Internal protein

A

VP4

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14
Q

Rhino or entero?
Acid stable
1.4 bouyancy
Stabilized by mgcl2

A

Entero
Rhino
Both

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15
Q

Enteroviruses are stable in ether , organic solvents since they do not contain ______ in their capsids

A

Lipids

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16
Q

Antibodies for entero appear the same when____

A

Symptoms appear

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17
Q

At what tissue does entero continue to replicate even high titers of antibody?

A

GIT

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18
Q

Polio viruses are inactivated by?

A

Heat and chlorine

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19
Q

Primary multiplication of polio

A

Oropharhngeal

Intestinal mucosa

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20
Q

Transmission and portal of entry?

A

Fecal oral

Mouth

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21
Q

Most common form of polio

A

Mild/abortive poliomyelitis

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22
Q

Present as stiffness in be back and neck

A

Nonparalytic/aseptic

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23
Q

Pm Flaccid paralysis?

A

Paralytic

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24
Q

Muscle wasting

A

Progressive post PM muscle atrophy

25
Q

Rarely used dx for polio

A

Serology!!

26
Q

Used for who eradication of polio campaign

A

OPV

27
Q

2 groups of coxsackie

A

A and B

28
Q

Most frequent serotype of group a cox

A

A9

29
Q

Diffuse myositis with necrosis of fibers of voluntary muscles (causing flaccid paralysis)

A

COx A

30
Q

Diseases of cox A

A

Herpangina
Hand foot and mouth disease
Acute hemorrhagic conjunctivitis

31
Q

Most commonly identified causative agebts of viral heart disease in humans

A

Cox B

32
Q

Diseases of Cox B

A

Pleurodynia
Myocarditis
Perocarditis
Severe generalized ds of infants

33
Q

Known as epidemic myalgia

A

Pleurodynia

34
Q

Known as vesicular pharyngitis

A

Herpangina

35
Q

Aseptic meningitis iS caused by all types of

A

Group a

Most common 7 and 9

36
Q

Abrupt onset of fever and sore throat, hyperemix pharynx vesicles on the post half of palate

A

Herpangina

37
Q

Ulcerations in herpangina is found in the

A

Posterior pharyngeal wall

38
Q

Vesicular rash on the palm and sole

A

Hand foot mouth ds

39
Q

HfmD ia caused by?

A

Cox A16

40
Q

Stabbing pain preceded by headache, anorexia, malaise; chest pain intensified by movt…. Caused by what?

A

Cox B

41
Q

Usually cause by a24 and entero 70

A

Acute hemorr conjunctivitis

42
Q

Enterovirus antigenically related to B5

A

Swine virus

43
Q

Meaning of echo virus

A

Enteric
Cytopathogenic
Human
Orphan

44
Q

Method of choice for isolation of ECHO

A

Monkey kidney cell culture

45
Q

Disease associated with ecHO

A

Aseptic meningitis
Rashes
Exanthem
Infantile diarrhea

46
Q

One of the main causes of cns disease

A

Entero 71

47
Q

Isolated in px w broncholitis

A

Entero 68

48
Q

Only cox B may cause

A

Diabetes/pancreatitis;

Pleurodynia

49
Q

Only cox a may cause?

A

Herpangina

Conjunctivitis

50
Q

Cox a, b and echo may cause?

A

Rash/ exanthem

51
Q

Neonatal ds obly cause by?

A

B and echo

52
Q

Consists of 6 types, others originally from echo; highly divergent with almost no protei identical to other picorna

A

Parecho

53
Q

Common cold viruses

A

Rhino

54
Q

Early symptom of colds

A

Chilliness

55
Q

Cause foot and mouth ds

A

Apthovirus

56
Q

Aphtho is acid labile at?

A

Ph below 7 (wow generAl talaga!)

57
Q

Causes in encep and myocarditis in RODENTS

A

Cardio

58
Q

Consists of 2 virus

A

Emcv (1 serotype)

Theilovirus

59
Q

True or false? Emcv results in cns involvement but NO myocarditis

A

True!!

Micro (24 decks)

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