4opportunistic Flashcards
Types of opportunistic
Saprophytic
Endogenous
Due to fungi of low virulence
Opportunistic
Most frequent opportunistic
Candida
Cryptococcus
Aspergillus
Mucor
Endogenous organism found in 40-80% normal human beings
Candida
Candida is found in? 4
Mouth
Skin
Gut
Vagina
Candida in culture ir tissue
Oval budding yeast
2 kinds of candida formationp
Pseudohyphae
Germ tube
C albicans form what morphology?
Germ tube
Moist opaque colonies, soft cream colored, what agar?
Blood agar at 1day body temp
3 clinical findings of candida?
Cutaneous/mucosal
Systemic
Mucocutaneous chronic
Examples of cutaneous candidiasis
Intertriginous
Oral thrush
Onychomycosis
Vulvovaginitis
Common in obese and diabetic individuals
Intertriginous
Patchy confluent whitish paeudomembranous lesion in tongue lips, gums; aids patients; corticosteroid and abx therapy
Oral thrush
Painful, erythematous swelling of nail fold
Onychomycosis
Yeast invasion of vaginal mucosa
Vulvovaginitis
Systemic candidiasis is caused by?
Catheters, surgery, drug abuse
Onset of chronic mucocutaneous candidiasis
Early childhood
Microscopic exam of candida, what to use?
KOH, calcofluor white
T or f? Sputum cultures has no value in candidiasis
T, part of normal flora
Rapid screening for c albicans
Germ tube test
Crucial for resistance to systemic candidiasis
Neutrophil
Treatment for systemic candidiasis
FC, fluconazole, caspofungin?
Ubiquitous saprophyte
Aspergillus
Most common aspergillus
Fumigatus
3 principal entities of aspergillus
Allergic bronhopulmonary aspergillosis
Pulmo aspergilloma
Invasive aspergillsis
Nosocomial infection is possible
Aspergillus
Morphology of aspergillus
Long condiosphore w terminal vesicle producing basipetal conidia
When aspergillus invades preexisting cavities
Fungus ball
Invasive aspergillosis may cause
Endocarditis
Osteomyelitis
Meningitis
Micro exam demonstrate hyaline dichotomously branching
Aspergillus
In ID presence of >=3 precipitin bands indicate
Severe dse
ID test not helpful in what aspergillus entity
Invasive aspergillosis
Treatment for aspergillus
Ampo B
Other term for mucormycosis
Zygomycosis
Mucormycosis is acute inflamm of what?
Blood vessels/soft tissues
Mucor is commonly found in?
Moldy bread!!
Major clinical form of mucormycosis
RhinocerebrAl infection
Follows inhalation of sporangiospores w invasion of lung parenchyma and VASCULATURE
Thoracic mucormycosis
Cottony colonies
Mucormycosis
Micro exam of mucor identification is based on?
Sporangial structures
Treatment for mucormycosis
Ampho B
Yeast with thick polysaccharide capsule
Cryptococcus neoformans
Cryptococcus is found in what?
Dry pigeon and chicken droppings
Morphology of crytococcus that may suppress t cell
Capsule
Additional virulence factor of cryptococcus
Phenoloxidase
Pathogenesis of cryptococcus
Inhalation;
Pulmo infection;
Meningoenceph
_____ begin w visual problems headache stiffness coma disorientation
Menindoenceph
Mass in mediastinum which may be mistaken for lymphoma
Cryptococcoma
How to demonstrate the capsule of cryotoccus?
P
India ink test
Std for meningo + cryptococcus
AmpHO B And FC