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Micro > 4-2 Rhabdo > Flashcards

4-2 Rhabdo Flashcards

0
Q

5 proteins encoded by genome?

A 
N
P
mP
G
L
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1
Q

Describe mononega

A

Non segmented
Ss rna
Nega

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2
Q

2 major structural proteins

A

Rnp

Envelope

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3
Q

Protein for neuroinvasiveness and pathogenicity

A

G

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4
Q

Mainly in wildlife in______ countries

A

Developed

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5
Q

2 epid forms

A

Urban

Sylvatic

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6
Q

Rare form of transmission

A

Aerosol in halation

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7
Q

T orF ? It is possible for rabies to go ditectly to the nervous system w/o local replication

A

T

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8
Q

Organ w highest titers of virus

A

Submaxillary

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9
Q

Specific eosinophilic inclusion body (pathognomonic)

A

Negri body

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10
Q

T or f? Absence of negri rule out rabies

A

F

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11
Q

2 forms of prodromal sx

A

Encephalitic

Paralytic (dumb)

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12
Q

What form has hydrophobia and aerophobia

A

Furious type

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13
Q

What kind of paralysis in dumb type?

A

Flaccid
Ascending
Symmetric

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14
Q

Most rapid skin biopsy

A

F aBs

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15
Q

TorF? There are pathognomonic findings in imaging?

A

F

16
Q

Biopsy specimen in humans obtained from? Animals?

A

Nape

Brain!

17
Q

T or F? Blood contains virus

A

F

18
Q

WHO categories of exposure?

A

1,2,3

19
Q

Mgt for cat1

A

Wash, no vaccine, preEP may be needed

20
Q

What category?

  • licks on broken mucosa
  • unprotected handling of carcass
  • ingestion of raw meat
  • sharing utensils w px
A

3
3
3
1

21
Q

Rig is only indicated in what cat?

A

3 plus cat2 if immunocompromised

22
Q

Thai red crosa Sked for active immunization

A

Day 0,3,7,28

23
Q

One dose should be at least ______ vaccine potency

A

0.5 IU

24
Q

Essen regimen?

A

Day 0,3,7,14,28

25
Q

0,0,7,21

A

Zagreb regimen

26
Q

0,7,30 (8 doses, 4doses, 1dose)

A

Oxford regimen

27
Q

How many RIG doses given ?

A

1

28
Q

If immunized mt 3 years, and ab titer is less than 0.5, booster needed?

A

Yes

29
Q

Bites requiring PEp

A

Domestic
Livestock
Wild animals

30
Q

Booster regimen

A

Day 0,3

31
Q

Specimen for antibody detection

A

Serum

Micro (24 decks)

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