Parvovirus

Question 0

Major capsid protein

Answer 0

VP2

Question 1

Helper virus for dependovirus

Answer 1

Adeno

Herpes

Question 2

Virions are exteemely resistant to inactivation: how?

Answer 2

Stable at pH 3-9
Heating at 56c for 1 hr
FBO chemicals (formalin, beta propionolactone, ox agents)

Question 3

Describe the genome

Answer 3

SsDNA, linear, naked, icosahedral

Question 4

Tropism of b19

Answer 4

Rbcs

Question 5

Cellular receptor for B19

Answer 5

Globoside

Question 6

Transmission?

Answer 6

Respi route

Question 7

Viremia when?

Answer 7

Before onset of rash and athralgia

Question 8

5 diseases of parvo b19

Answer 8

5th disease
Polyarthropathy syndrome
Transient aplastic
Persistent anemia
Hydrops fetalis

Question 9

Slapped cheek appearance

Answer 9

5th disease

Question 10

Transient aplastic crisis may occur in individuals with?

Answer 10

Sickle cell anemia
G6PD
Spherocytosis

Question 11

Arthropathy that occurs in adults than children and women than men

Answer 11

Polyarthropathy syndrome

Question 12

Chronic suppression of bone marrow

Answer 12

Pure red cell aplasia

Question 13

Maternal fetal transmission of this leads to?

Answer 13

Hydrops fetalis

Question 14

Used to detect b19 antigens in fetal tissue and in bone marrow

Answer 14

Immunochemistry

Question 15

Only assay available for bocavurus

Answer 15

Pcr