4B-5 Filo Flashcards
0
Q
4 subtypes of ebola
A
Sir z Sudan Ivory coast Reston Zaire
1
Q
Two known filo that are antigenically distinct
A
Marburg
Ebola
2
Q
4 subtypes differ only by___%
A
40
3
Q
Genome of filo?
A
RENN
Rna ENVELOPED negative strand nonsegmented
4
Q
Evelope GP is encoded how?
A
2 reading frames and become trimer spikes!
5
Q
T or F?Infections from these tend to be immunosuppressive?
A
T
6
Q
How are filo deactivated
A
Heat 30 mins 60.C
UV and gamma rad
Lipid solvent
Bleach and phenolics
7
Q
Tropism for?
A
Immune response cells
8
Q
Resevoir host of marburg and ebola
A
Rodent/bat
9
Q
Aftican hemorrhagic fever seen w?
A
Marburg and ebola
10
Q
Subtype that possess low pathogenicity to humans
A
Reston
11
Q
T or F? Filo can be cultured in cell lines
A
T
