Polyarteritis nodosa Flashcards
1
Q
What is it?
A
a vasculitis affecting medium-sized arteries with necrotizing inflammation leading to aneurysm formation
2
Q
Who?
A
more common in middle-aged men and is associated with hepatitis B infection.
3
Q
which infection is it associated with?
A
hep B
4
Q
features
A
fever, malaise, arthralgia
weight loss
hypertension
mononeuritis multiplex, sensorimotor polyneuropathy
testicular pain
livedo reticularis
haematuria, renal failure
perinuclear-antineutrophil cytoplasmic antibodies (ANCA) are found in around 20% of patients with ‘classic’ PAN
hepatitis B serology positive in 30% of patients
