ANKYLOSING SPONDYLITIS Flashcards
Which antigen is it associated with?
HLA-B27
epidemiology
men
aged 20-30 years
features
man lower back pain and stiffness
stiffness worse in morning
improves with exercise
patient experiences pain at night which improves on getting up
onset
insidious
clinical exam features
reduced lateral flexion
reduced forward flexion - Schober’s test - a line is drawn 10 cm above and 5 cm below the back dimples (dimples of Venus). The distance between the two lines should increase by more than 5 cm when the patient bends as far forward as possible
reduced chest expansion
other features - the A’s
Apical fibrosis
Anterior uveitis
Aortic regurgitation
Achilles tendonitis
AV node block
Amyloidosis
cauda equina syndrome
peripheral arthritis (25%, more common if female)