Pituitary Function & Failure Flashcards

0
Q

anterior pituitary comes from what?

A

glandular/ectodermal cells hence vascular link

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1
Q

Posterio pituitary comes from what tissues?

A

outgrowth of brain hence neural link to hypothalamus

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2
Q

stalk of pituitary called?

A

infundibulum

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3
Q

posterior pituitary release?

A
  1. ADH/Vasopressin

2. Oxytocin

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4
Q

posterior pituitary hormones released from endings of what nerves?

A

supraoptic

paraventricular neurons

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5
Q

Anterior pituitary release?

A
FSH
LH
ACTH
TSH
Prolectin
GH
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6
Q

what inhibits prolactin?

A

Dopamine (Prolactin inhibiting hormone)

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7
Q

Somatostatin does what?

A

inhibit GH

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8
Q

GnRH does what?

A

stims FSH and LH

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9
Q

ACTH acts on what?

A

adrenal cortex

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10
Q

corticotropin releasing hormone does what?

A

from hypothalamus and stims ACTH in anterior pituitary

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11
Q

What can inhibit CRH in its negative feedback loop?

A

ACTH and the Cortisol

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12
Q

What does somatomedin affect?

A

bone

soft tissue

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13
Q

LH does what?

A

sex hormone secretion:
estrogen/progesterone
testosterone

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14
Q

FSH stims?

A

gamete production
egg
sperm

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15
Q

hypothalamus is affected by what?

A

higher centres like sight, smell, etc.

limbic system

16
Q

decreased protein binding could lead to what kind of endocrine disorder?

A

hypersecretion (more free hormone)

17
Q

What is Kallmann syndrome?

A

embryology GnRH neurons fail to migrate

18
Q

What is somatotropin?

A

GH

19
Q

effects of GH compared to insulin?

A

increase blood fatty acid and glucose

20
Q

GH half life?

A

18 minutes

21
Q

what are somatomedins?

A

IGF 1 and 2 (poly peptide growth factor)

22
Q

what hormone closes the epiphyseal plates of long bones?

A

estrogen

23
Q

what is Laron dwarfism?

A

GH receptor insensitivity (liver)

24
Q

chronic abuse or neglect can cause abonormal growth?

A

psychsocial dwarfism