Hormone Measurement Interpretation Flashcards
What does the TSH and FT4 look like in the failing thyroid?
TSH is raised above normal before FT4 is below normal
What hormone test to test water?
ADH
how is Reference range defined?
95% of a ‘normal’ population
may vary
what’s the cholesterol reference range idea?
there is a difference between population ‘normal’ and the ideal. The entire population may be slightly more cholesterol
what is a dynamic test? 2 things
- sampling at multiple times
2. stimming or suppressing
when use dynamic testing?
if looking for subclinical disease
what do you use instead of dynamic testing these days?
hormone imunoassays
What does dexamethasone suppression test test?
adrenals
measure cortisol
if you have an abnormal dexamethasone test, could suggest?
Cushing’s Syndrome
What is Synacthen test used for?
stimming adrenals to measure cortisol
how to measure low levels of hormones technique?
Immunoassays
2 kinds of immunoassays
- non-competitive (sandwich)
2. competitive
In a competitive immunoassay, would you get a strong signal with high hormone concentration?
Nope, weaker signal
In non competitive immunoassay, increased hormone concentration gives you?
higher signal detection
Can you test for free hormones in blood?
harder, not usually
