Endocrine Control/Review Flashcards

0
Q

what is a temporary endocrine gland?

A

placenta

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1
Q

Hormone is borne where? acts where?

A

blood borne
comes from endocrine glands
acts on distant targets

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2
Q

What is neurocrine?

A

signal from a neuron down its axon via blood to distant target

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3
Q

All Hormones only produced by their respective glands?

A

Nope, multiple endocrine glands can make same hormones

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4
Q

each hormone only has a single target?

A

Nope, multiple target and function

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5
Q

purpose of autocrine and paracrine?

A

extracellular messages

local communication

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6
Q

Lipophilic is also?

A

Hydrophobic

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7
Q

Hydrophilic also equals

A

lipophobic

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8
Q

why is permeability and solubility important?

A

in terms of location of receptors

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9
Q

Neurotransmitters use for transmitting what kind of message?

A

rapid, localised, specific, smaller distance

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10
Q

Neurohormones are secreted by? into?

A

by neuron

into blood stream

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11
Q

3 examples of neurohormones

A
  1. hypothalamus to ant. pit and 2. post. pit

3. catecholamines

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12
Q

catecholamines made where? by what?

A

made by neurons

modified adrenal medulla

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13
Q

What is a tropic hormone?

A

a hormone that controls secretion of another hormone

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14
Q

Two big hormone receptor types?

A

GPCR

Tyrosine Kinase-linked receptors

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15
Q

Peptide hormones release is how? solubility?

A

exocytosis, hydrophilic

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16
Q

Peptide hormones half life?

A

short

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17
Q

Peptide hormones receptor location?

A

cell membrane

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18
Q

2 examples of Peptide hormones?

A

insulin

parathyroid

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19
Q

Steroid hormones release and solubility?

A

simple diffusion

lipophilic

20
Q

Steroid hormones synthesis/storage?

A

made on demand from cholesterol

21
Q

peptide hormones synthesis and storage?

A

made in advanced and stored in secretory vesicles

22
Q

Steroid hormones location of receptor

A

cytoplasm or nucleus

23
Q

eg. of Steroid hormones?

A

androgens
estrogen
cortisol

24
Q

catecholamines synthesis and storage?

A

made in advance and stored

25
Q

catecholamines release and solubility?

A

exocytoic

hydrophilcic

26
Q

catecholamines half life?

A

short

27
Q

steroid hormones half life?

A

long

28
Q

catecholamines receptor target?

A

cel membrane

29
Q

catecholamines receptor response?

A

2nd messenger syetm

30
Q

eg. of catecholamines? 2?

A

epinephrine

norepinephrine

31
Q

Thyroid hormones half life?

A

long

32
Q

Thyroid hormones release and solubility?

A

simple diffusion

lipophilic

33
Q

peptide hormones in the ER are created as a?

A

Prohormone

34
Q

The peptide hormone is active or inactive in the storage vesicles?

A

active

35
Q

what is a precursor molecule to catecholamines and thyroid hormones?

A

Tyrosine

36
Q

What two kind of hormones generate 2nd messengers?

A

peptide

catecholamines

37
Q

Thyroid hormones travel how through blood stream?

A

bound to TBG

38
Q

how are steroid hormones removed?

A

conjugation > urination

39
Q

Amine hormones are removed how?

A

specific degrading enzymes

40
Q

how are large peptide hormones removed?

A

receptor-mediated endocytosis

41
Q

how are smaller peptide hormones removed?

A

kidneys

42
Q

Positive feedback loop example?

A

labour and LH surge

43
Q

2 ways to regulate hormone secretion

A
  1. neuroendocrine reflexes

2. feedback

44
Q

Pineal gland makes?

A

Melatonin

45
Q

What is permissive hormone regulation?

A

first hormone can’t affect without presence of second hormone

46
Q

eg. of hormone antagonism?

A

insulin

glucagon

47
Q

2 ways to down regulate hormone secretion

A
  1. endocytosis

2. target cell desensitisation

48
Q

primary vs. secondary endocrine disorder?

A

primary: gland itself
secondary: excessive or abnormal stim