Pigments Quiz #2 Flashcards
where do exogenous pigments originate?
out side the body
where do endogenous pigments originate?
inside the body
what is the MC exogenous pigment?
coal in the air in big cities
What is accumiliation of coal in the lungs of coal mine workers is known as?
anthrocosis
what is another form of exogenous pigment placed on the skin?
tatoo
engogenous pigments that are yellow and brown are known as?
lipofuscin
What is the aka for “wear and tear” pigment?
brown atrophy
what is melanin?
black pigment
what amino acid is malanin derived from?
tyrosine
what is homogenistic acid?
pathological black pigment
Pathological intermediate that accumilates as normal metabolic intermediate?
alkaptonuria
what is hemadosiderin?
iron storage complex within the form of ferritin micells
what is hematosideris?
excess accumilation of iron; upto 50 grams
can be gentic or acquired
what is primary hemochromatosis?
gentic disease
what three characteristics of primary hemochromatosis?
liver fibrosis
pancrease damage
dna damage
what is secondary iron overload?
acquired systemic overload
what is an example of secondary iron overload?
bantu siderosis
what is hepatoma?
liver cancer
what is kayser fleischer?
copper that accumilates in the eyes
how can keiser-fleischer be treated?
D-penicillamine
what is calcification?
deposition of calcium in the tissue
what is dystrophic calcification?
deposition of calcium in necrotic tissue
what is ghon’s pox?
area of granuloma and inflammation in the lungs
attempt to kill mycrobacerium bacilli=tissue goes undercalcification and can be seen on xray
what is sclerodactily?
too much CT in the body replaCING FUNCTIONAL tissue seen in hands and face (no smile)
what causes vulvular disease?
fibrinoid necrosis
what is fibriniod necrosis?
seen in rheumatiod arthritus causes atrophy of the valves
where is calcium deposited in the heart?
aortic valves
what if ischemia happens in the brain?
stroke (liquefaction)
what if ischemia happens in the heart?
myocardial infarction (coagulation)
what organ is least vulnerable to ischemia?
liver
what is hypoxia?
lack of oxygen to the tissue
with regard to ionizing radition, what tissue is the most sensitive?
epithelial cells of the GI tract
what cells are the least effected by ionizing radiation?
bone
with regards to viral infection, what is HIV?
attacks T-helper lyphocyte cells and macrophages
what is polio virus?
impairs the function of anterior horns of the spinal chord resulting in lack of neurological stimulus of muscles
what is human papilloma?
promotes the development of cervical cancer
what is hepatitus?
has tropism towards hepatocytes
