Hemodynamic Disorders

Question 1

What is a thrombosis?

Answer 1

platelet activation (von willibrand factor is working) and platelet aggregation occurs without threat of vascualr damage and blood loss

Question 2

what is the result of a thrombosis?

Answer 2

platelet plug formation

Question 3

where may a bood clot form?

Answer 3

inside or outside of a vessel

Question 4

where may a thrombus form?

Answer 4

refers to blood that has clotted within a blood vessel and always maintains a point of contact

Question 5

where does a thrombus originate?

Answer 5

from a vascular wall

Question 6

what are the lines of Zahn?

Answer 6

thrombi characterized by visible and microscopic lamination produced by alternating layers

Question 7

what is a plae layer composed of?

Answer 7

platelets mixed with fibrin

Question 8

what is the dark layers composed of? in the Lines of Zahn?

Answer 8

composed of RBC

Question 9

where can the lines of Zhan be found?

Answer 9

heart and usually the arch region

Question 10

what is an exmaple of Lines of Zhan?

Answer 10

mitral stenosis: narrowong of the left atrioventricular opening–>bllod flow is slower

Question 11

what is the first factor in thrombosis formation?

Answer 11

endothelial damage

Question 12

what causes hemodynamic stress (aka: normal wear and tear)?

Answer 12

hypertension

Question 13

what is hypertension?

Answer 13

increaased resistance and friction between vasculature wall and fluids

serois facor that promotes endothelial damage

Question 14

what is arterial hemodynamic stress?

Answer 14

normal wear and tear resulting in arteriosclerosis accerlated by hypertension

Question 15

what is atherosclerosis?

Answer 15

specific changes such as formation of plaque in arterial walls

Question 16

what does platelet aggregation lead to?

Answer 16

atherosclerotic plugs

Question 17

what is venous iatrogenic thrombosis?

Answer 17

caused by medical care–>results in endothelial damage

Question 18

where does thrombosis usually occur?

Answer 18

95% happen in the deep veins due to slow blood flow

Question 19

what are characteristics of flow abnormalities?

Answer 19

reduction in the rate of blood flow

Question 20

what causes decreased rate of blood flow?

Answer 20

cardiac damage

Question 21

what is mitral stenosis?

Answer 21

narrowing of the valve reduces blood flow–>thrombus formation in the lines of Zhann

Question 22

what is a mural thrombosis?

Answer 22

formed in the chambers in the heart

Question 23

what is rhuematic heart disease?

Answer 23

mitral stenosis slows blood flow in the lft atrium and thrombus formation likely

Question 24

what is increased blood viscosity?

Answer 24

changes blood properties–> causes blood to slow slower–>predisposition to thrombus

Question 25

what is polycythemia?

Answer 25

over production of red blood cells—>increases furiction to vascular wall–>can lead to death

Question 26

where is a thrombus MC in venous system?

Answer 26

lower legs deep vein

Question 27

how do the valaves open in the veins?

Answer 27

sub P/vasodilator

Question 28

what are varacose veins?

Answer 28

disention in the vein walls from each other; valves are not closing properly

flow goes without restriction

Question 29

what is turbulence?

Answer 29

disruption of laminar blood flow

Question 30

what is hypercoagulation?

Answer 30

increased ability of the blood to coagulate