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Pathology I > Necrosis > Flashcards

Necrosis Flashcards

1
Q

what is the definition of necrosis?

A

a condition of cell death thru injury of diseases, especially ina localized area of the body

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2
Q

whatv poart of the cell goes under digestion?

A

cytoplasm

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3
Q

What does the lysosome of the necrotic cell release?

A

lysosomal enzymes

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4
Q

what is coagulative necrosis?

A

implies the preservation of basic outline of the coagulated cell for period of at some days

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5
Q

what 3 things is necrosis characterized by?

A

a. denature of cyto plasmic proteins
b. break down of cell organelles
c. cell swelling

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6
Q

what is white infartion?

A

single blood supply

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7
Q

what is red infarction?

A

dual blood supply

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8
Q

what is liquefactive necrosis?

A

complete digestion of cells resulting in transformation of tissue into a liquid viscous mass

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9
Q

what is an example of liquefactive necrosis?

A

ischemic stroke of the brain

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10
Q

wha t is casseous necrosis?

A

amorphous granular debris seemingly composeed of fragmanted coagulated cells

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11
Q

what is amorphous granular debris?

A

enclosed within a distictive site inflammatory border known as granulomatous reaction

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12
Q

what does granuloma mean?

A

collection of immune cells that are trying to get rid of a foreign substance

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13
Q

what are examples of casseous necrosis?

A

TB and leprosy

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14
Q

what is gummatous necrosis?

A

develops only in syphilis

death of tissue is caused by treponema pallidum

usually acquired by sexual transmission

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15
Q

what is primary syphilus?

A

single chancre

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16
Q

what is secondary syphilus?

A

involves skin usually hands and feet

17
Q

what is tertiary syphilus?

A

involves the aorta 80-85% of the time years later

and involves the CNS 5-10% of the time

18
Q

What part of the spine does tertiary effect?

A

the posterior columns

19
Q

what name does it receive when effecting the posterior columns?

A

tabes dorsalis

20
Q

what is the name when the grey matter is atrophied?

A

general paesis

aka general paresis of insane

21
Q

what are characteristics of Zenkers necrosis?

A

glassy waxy necrosis of the skeletal muscle

22
Q

what is zenker’s necrosis (the disease) called?

A

typhiod fever

23
Q

how do you contract zenkers necrosis?

A

salmonella bacteria

can also be caused by a snake bite

24
Q

what is fat necrosis?

A

necrosis of the adipose tissue

characterized by small quantities of soap bubbles

25
Q

where does fibriniod necrosis occur?

A

in the walls of blood vessels when edothelial cells and smotth muscle cells are injured/dying

26
Q

what is an example of fibrinoid necrosis?

A

Aschoff’s nodes; seen in rhuematic fever

27
Q

what is gangrene necrosis characterized by?

A

anaerobic bacterial metabolism

28
Q

what causes dry gangrene ischemia?

A

lack of oxygen supplied to an organ or tissue

29
Q

dry gangrene in the distal parts of the body is known as?

A

systemic sclerosis

30
Q

what is atherosclerosis?

A

Buerger’s disease

affects nerves and veins not arteries

caused by smoking

31
Q

what is dry gangrene diabetes mellitus?

A

obliteration of the distal small vessels

32
Q

what is wet gangrene?

A

phagocytic cells break down the necrotoc debris and produce some liquefaction

33
Q

what causes wet gangrene?

A

anaerobic bacteria

clostridium perfringes and bacillus fusiform

34
Q

Wet gangrene in the distal parts of the fingers in known as?

A

polyarteritis nodosa

35
Q

what causes intestinal gangrene?

A

anaerobic bacteria

36
Q

what is gas gangrene?

A

bacterial infection that produces gas within tissue

common inthe military

37
Q

what causes gas gangrene?

A

clostridium perfrimges

anaerobic streptoccocci

Pathology I (21 decks)

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