Pigmentation disorders

Question 1

Vitiligo- Eti

Answer 1

Destruction of melanocytes beginning between age 10-30, heritable, chronic slow progressing

Question 2

Vitiligo- Sx

Answer 2

Enlarging depigmentation with sharp borders. common on extensor surfaces, skin folds

Question 3

Vitiligo- Dx

Answer 3

Clinical

Question 4

Vitiligo- Tx

Answer 4

Photochemotherapy

Question 5

Albinism-Eti

Answer 5

Genetic disorder due to deficient tyrosinase activity in melanocytes

Question 6

Albinism- Sx

Answer 6

Oculocutaneous depigmentation- white hair, translucent irises

Question 7

Albinism- Tx

Answer 7

None available

Question 8

Melasma-Eti

Answer 8

Acquired brown hyper pigmentation from sunlight exposure. Hormones and meds play role

Question 9

Melasma- Sx

Answer 9

uniform, macular hyper pigmentation typically on face

Question 10

Melasma- Tx

Answer 10

Prevention: sunblock. Tx: hydroquinone, azelaic acid

Question 11

Postinflammatory hyperpigmentation– Eti

Answer 11

Darkening of skin following dermatologic condition- more common in darker skin

Question 12

Postinflammatory hyperpigmentation– Sx

Answer 12

Hyperpigmented macules appearing following dermatologic disorder

Question 13

Postinflammatory hyperpigmentation-Tx

Answer 13

Hydroquinone accelerates depigmentation