Malignant lesions

Question 1

Basal cell carcinoma- Eti

Answer 1

Most common cancer. Onset >40, males. Skin types 1 & II

Question 2

Basal cell carcinoma- Sx

Answer 2

Nodular: pearly papule with telangiectasias, well defined & firm
Ulcerating: Crust with rolled pearly border with telangiectasias
Sclerosing: Ill defined patch or superficial scar with peppery pigmentation, finger like extension
Superficial:thin plaques, thread like borders & telangictatsias and scaling
Pigemented: Brown/blue/black, smooth pearly surface, umbilicated cystic

Question 3

Basal cell carcinoma- DX

Answer 3

Atypical basal cells histologically

Question 4

Basal cell carcinoma- Tx

Answer 4

Excision with primary closure, flaps or grafts

Question 5

Bowen disease- Eti

Answer 5

AKA squamous cell carcinoma in situ. UVR or HPV induced lesions. Sun & non-sun exposed areas.

Question 6

Bowen disease-Sx

Answer 6

Sharply demarcated, scaling surface/ erosion, pink to red macule, papule, or plaque. Bleeds easily

Question 7

Bowen disease- Dx

Answer 7

Biopsy-

Question 8

Bowen disease-Tx

Answer 8

5-florouracil cream, cryo, excision

Question 9

Paget disease- Eti

Answer 9

Neoplasm of anogenital and axillary skin. Common with underlying Gu/GI CA. Epidermal extension of underlying apocrine glands

Question 10

Paget disease- Sx

Answer 10

Slowly spreading, itchy lesions- scaling plaque with erosion, crusting. Sharply defined borders

Question 11

Paget disease- Dx

Answer 11

Biopsy

Question 12

Paget disease- Tx

Answer 12

Surgical removal- Mohs

Question 13

Squamous cell carcinoma- Eti

Answer 13

Prolonged sun exposure, very common, fair skin and organ transplant recipients

Question 14

Squamous cell carcinoma- Sx

Answer 14

Ulcerating, small red conical hard nodules

Question 15

Squamous cell carcinoma- Dx

Answer 15

Biopsy

Question 16

Squamous cell carcinoma-Tx

Answer 16

Mohs excision