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SMB II > Acne- Pharm > Flashcards

Acne- Pharm Flashcards

1
Q

Benzoyl Peroxide- Indications

A

Mild, mixed acne- inflammatory & comedones

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2
Q

Benzoyl Peroxide- MOA

A

Unknown- keratolytic & antibacterial

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3
Q

Benzoyl Peroxide- AE

A

Contact dermatitis, xeroderma, erythema, peeling

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4
Q

Retinoids- Indications

A

Mild non to mild mixed acne

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5
Q

Retinoids- MOA

A

Unknown- epithelial cell turnover

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6
Q

Retinoids- Names

A

Tretinoin, adapalene

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7
Q

Retinoids- AE

A

Photosensativity, peeling, zeroderma, bruning, erythema, pruritis

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8
Q

Clindamycin Topical- Indications

A

Mild mixed to deep inflammatory acne

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9
Q

Clindamycin Topical- MOA

A

Inhibits P. acnes- antiinflamatort

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10
Q

Clindamycin Topical- AE

A

Increased resistance. Use in conjunction with BPO.

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11
Q

Erythromycin Topical- Indications

A

Mild to moderate acne

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12
Q

Erythromycin Topical-MOA

A

Antimicrobial and anti-inflammatroy

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13
Q

Erythromycin Topical- AE

A

Increased resistance. Use in conjunction with BPO.

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14
Q

Tetracycline- AE

A

Pregnancy & children with out all adult teeth- tooth discoloration

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15
Q

Tetracycline- Indications

A

Moderate to severe acne

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16
Q

Moderate to severe acne MOA

A

Antimicrobial & anti-inflamatory properties

17
Q

Minocycline- Indications

A

Deep inflammatory, moderate, non-scarring acne, in conjunction with topical abx.
More effective than tetracycline

18
Q

Minocycline- MOA

A

Bacteriostatic, inhibits protein synthesis

19
Q

Minocycline- AE

A

Resistance, candidiasis, GI, HA

20
Q

Doxycycline- Indications

A

Deep inflammatory, moderate, non-scarring acne, in conjunction with topical abx.

21
Q

Doxycycline- MOA

A

Bacteriostatic, inhibits protein synthesis

22
Q

Doxycycline- AE

A

photosensitizing, same but fewer than minocycline

23
Q

Tetracycline- Indication

A

Deep inflammatory, moderate, non-scarring acne, in conjunction with topical abx.

24
Q

Tetracycline- MOA

A

Bacteriostatic, inhibits protein synthesis

25
Q

Tetracycline- AE

A

more common than other orals, must take on empty stomach- no dairy

26
Q

Macrolides- Indications

A

Moderate to severe acne

27
Q

Macrolides- MOA

A

antimicrobial & anti-inflammatroy

28
Q

Macrolides- AE

A

GI distress, hepatotoxicity

29
Q

Isotretinonin- Acutane- Indications

A

Severe nodulocystic acne, resistance to conservative tx

30
Q

Isotretinonin- Acutane- MOA

A

Decreases sebum production, not well understood

31
Q

Isotretinonin- Acutane- AE

A

-Teratogenicity!!
xerosis, chelitis, blepharconjunctivitis, epitaxis
- depression/ suicide?
-IBD?
- Elevated liver enzymes, myaglia, arthralgia elevated triglycerides

32
Q

Isotretinonin- Acutane- Pt Ed

A

Must not become pregnant- category X, depression/ suicide risk. Must be on 2 contraceptives, monthly monitoring

33
Q

Oral contraceptives- Indications

A

Females for flares, persistant inflammatory papules on jaw, neck, back

34
Q

Oral contraceptives- Types

A

Spironolactone- potassium sparing diuretic

BCP- suppress androgen production

35
Q

Salicylic acid- Indications

A

Mild, non-inflammatroy acne

36
Q

Salicylic acid- MOA

A

keratolytic, epidermal cell removal

37
Q

Salicylic acid- AE

A

Irritation, stinging, burning, acidosis or alkalosis

SMB II (16 decks)

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