PICORNAVIRIDAE Flashcards
“Pico” means?
Very small
Describe the genome of Picornaviridae.
Positive-sense single-stranded RNA
Describe the morphology of Picornaviridae.
Small non-enveloped
Picornaviridae is resistant to many ____ solvents.
organic
Viral RNA of Picornaviridae is translated into a ____ before processing.
polyprotein
How many genera are under Picornaviridae?
29 genera
It is the genus that is considered the largest.
Genus Enterovirus
Capsid of Picornaviridae has 4 structural proteins. Which one is for receptor binding, uncoating and antigenicity?
VP1
Capsid of Picornaviridae has 4 structural proteins. Which one is for structural integrity and immune recognition?
VP2 and VP3
Capsid of Picornaviridae has 4 structural proteins. Which one is for RNA encapsidation and uncoating/pore formation?
VP4
FMD virus belongs to what genus?
Genus Aphthovirus
Give the 7 serotypes of FMD.
- A
- O
- C
- SAT 1
- SAT 2
- SAT 3
- Asia 1
Give the clinical signs of FMD virus in cattle.
o Incubation period: 2-8 days
o Fever, loss of appetite, depression, marked decrease in milk production
o Drooling of saliva, vesicles develop on tongue and gums
o Vesicles in interdigital skin and coronary band of the feet and teats
o Myocardium and myocarditis in calves
o May abort
Give the clinical signs of FMD virus in swine.
o Lameness – first sign
o Severe foot lesions
o Vesicles within the mouth
What is the main route of infection of FMD virus?
- Inhalation of droplets
- Others: ingestion of infected food, in
contaminated vaccines, semen, clothing, instruments
Swine Vesicular Ds. Virus is reclassified as ?
Enterovirus B
Swine vesicular ds. virus is genetically very similar to ?
Human coxsackievirus B5
Swine vesicular ds. virus has been estimated to move from humans to animals. What is this phenomenon called ?
Anthroponosis or zooanthroponosis
Swine vesicular ds. virus has resistance to ?
Low pH and ambient temp.
Swine vesicular ds. virus can be transmitted via meat. True or False?
True
What are the clinical signs of Swine Vesicular ds. virus?
- Disease is often detected by the sudden appearance of lameness in several swine in a herd
- Vesicle formation began by day 2 after exposure
What is the transmission route of Swine vesicular ds. virus?
Fecal oral route
Porcine Teschovirus 1 (Teschovirus A) causes what ds.?
Porcine polioencephalomyelitis
What is the transmission route of Porcine Teschovirus 1?
Fecal-oral route
