ARTERIVIRIDAE Flashcards
Describe the morphology of Arteriviridae.
- Enveloped, spherical
- Nucleocapsid are isometric
- Small indistinct glycoprotein spikes compared to prominent spikes of coronaviruses
Describe the genome of Arteriviridae.
Linear positive-sense, single-stranded RNA
How many nucleocapsid protein are present in Arteriviridae?
1
Give the 7 envelope proteins of Arteriviridae.
- E
- GP2
- GP3
- GP4
- ORF5a
- GP5
- M
Host range of Arteriviridae is ?
Highly restricted
Virions of Arteriviridae replicate in what type of cell?
Macrophages
Give the clinical signs induced by Equine arteritis virus.
- Systemic influenza-like ds.
- Arteritis
- Abortion
- Pneumonia in foals
- Progressive pneumo-enteric symptoms
- Abortion storms
What are the colloquial names of Equine Arteritis Virus?
- Pinkeye
- Infectious or epizootic cellulites
- Influenza erysipelatosa
- Pferdestaupe
What are the routes of transmission of Equine Arteritis Virus?
- Respiratory route
- Venereal route
Equine arteritis virus initial replication takes place in ____ ____ and ____ cells after aerosol respiratory infection.
alveola macrophages; endothelial
What are the characteristic lesions of Equine Arteritis Virus?
- Edema
- Congestion
- Hemorrhage
Give the diagnostic methods of Equine Arteritis Virus.
- Virus isolation
- RT-PCR in nasal or conjunctival swabs and whole blood, fetal tissues
Porcine Reproductive and Respiratory Syndrome Virus is initially designated as ?
Mystery swine ds.
What are the clinical signs induced by PRRSV?
- Hyperpneic
- Dyspneic
- Hyperemia
- Cyanosis of extremities
What are the clinical signs induced by PRRSV in sows?
- Reproductive failure
- SMEDI
What are the transmission routes of PRRSV?
- DIrect contact
- Inhalation of infectious aerosols
- Ingestions of virus-contamiated food
PRRSV primarily replicates in ____ in the lungs and ____ tissues of infected pigs.
macrophages; lymphoid
What are the characteristic lesions of PRRSV?
- Lymph node enlargement
- Interstitial pneumonia
What is the host of Lactate dehydrogenase-elevating virus?
Mice
Give the diseases induced by Lactate dehydrogenase-elevating virus.
Usually none, but the presence of the virus may confound research using infected mice
What is the host of Simian Hemorrhagic Fever Virus?
Macaques
What is the host of Wobbly possum disease virus?
Australian brushtail possum
Give the diseases induced by Wobbly possum ds. virus.
Neurologic ds.
Give the ds. induced by Simian Hemorrhagic Fever virus.
Systemic hemorrhagic ds., death
