INTRODUCTION TO VIRUSES: BRIEF HISTORY, CLASSIFICATIONS, & REPLICATIONS Flashcards
The capsid together with the enclosed nucleic acid core
Nucleocapsid
Choose between the three: 1. Parvoviruses; 2. Picornaviruses, 3. Herpesviridae and Paramyxoviridae
It comprises viral proteins and RNA.
Picornaviruses
Which was the year of reemergence of Ebola in West Africa?
2014
These are filterable agents that could not be cultivated on artificial media.
Virus
Who developed the Baltimore classification system?
David Baltimore
When and who discovered foot and mouth disease caused by filterable agent?
1898, Loeffler and Frosch
When and who discovered Myxoma virus?
1898, Sanarelli
In Retroviruses, what is its essential component to make the reverse transcriptase reaction?
tRNA
Give 3 single-stranded DNA viruses.
- Anelloviridae
- Circoviridae
- Parvoviridae
Viruses contain only one type of nucleic acid that carries the information for replicating the virus. True or False?
True
Ivanovsky and Beijerinck work on transmission of what virus?
Tobacco mosaic virus
More complex virions include the nucleocapsid and envelope. True or False?
True
What are the two main classification systems of virus?
- ICTV (International Committee on Taxonomy of Viruses)
- Baltimore classification system
Morphologic units composed of structural units embedded in the envelope
Peplomers
When was Middle East respiratory syndrome recognized?
2012
Retroviridae contains two whole-genomic negative-sense RNA’s. True or False?
False, positive sense
Complete infective virus particle; may be identical to the nucleocapsid.
Virion
When and who discovered Canine distemper virus?
1905, Carre
Give 2 single-stranded RNA viruses that has reverse transcriptase.
- Metaviridae
- Retroviridae
Give the hierarchy of ICTV classification system.
- Order (virales)
- Family (viridae)
- Sub-family (virinae)
- Genus (virus)
- Species
When and who discovered interferons?
1957, Isaacs and Lindemann
When did the sever acute respiratory syndrome outbreak occurs?
2002
The classes of Baltimore classification system is based on ?
Genome type and mode of replication and transcription
The major type of protein present on the exterior of the membrane of enveloped viruses/
Glycoproteins