physiology of the pulmonary system Flashcards
1
Q
what are the four steps involved in gas transport from atmosphere to the tissue
A
- ventilation: inspired air to alveoli
- external respiration: transfer from alveoli to capillary (diffusion)
- Transport: gas transport in blood to tissue
- internal respiration: exchange of gases between the capillary and tissue mitochondria
2
Q
Circulation
A
- passage of blood through the heart, blood vessels, organs and tissue
- transport system
3
Q
perfusion
A
- refers to the blood flow at the capillary level
- without this you get cyanotic
4
Q
ventilation
A
mechanical movement of gas in and out of the lungs (getting to and from alveoli)
5
Q
respiration
A
- exchange of O2 and CO2 across a membrane at the cellular level
- occurs via diffusion across a semipermeable membrane
6
Q
compliance
A
- a measure of the lungs ability to stretch and expand
- COPD = high compliance
- decreased compliance in restrictive pulmonary diseases
7
Q
Elasticity
A
- refers to the lungs ability to return to initial size after distension
8
Q
Surfactant
A
- a lipoprotein that REDUCES surface tension to keep alveoli open
9
Q
Partial pressure
A
- portion of the total pressure exerted by the presence of a single gas molecule
10
Q
Neural control of breathing
A
- automatic by pons (rate) and medulla (depth)
- voluntary = cerebal cortex (integrates with singing, talking, laughing)
- influenced by the hypothalamus (pH) and limbic system (emotion)
11
Q
Vagus nerve and respiration
A
- has stretch receptors to monitor when it is overstretched
- irritant receptors to initiate coughing
- j receptors
- hiccups stem from stimulation of the vagus nerve
12
Q
chemical control
A
- chemoreceptors in the brainstem, peripheral arteries, carotids and aorta
- sense changes in oxygen and carbon dioxide and pH
- more sensitive to CO2 changes
- feed into pons and medulla
13
Q
when is dyspnea most likely to occur
A
- when there is a discrepancy between neural drive to breathe and the level of ventilation achieved
14
Q
Describe the pump handle and bucket handle effects
A
- pump handle: refers to the up/anterior movement of the sterum and ribs
- bucket handle: refers to the lateral movement of the rib cage
15
Q
Mechanisms of inhalation
A
- the diaphragm contracts and moves down
- external intercostals contract lifting/rotating ribs, lift sternum and thoracic vertebrae
- lungs stretch
- pressure inside lungs is lower than pressure outside
- air gets pulled into lungs
- diaphragm pushes down into abdominal contents = abdomen expands