Oxygen saturation and Arterial Blood gasses Flashcards
What is oxygenation dependent on
- amount of hemoglobin
- partial pressure of oxygen
- amount of oxygen bound to hemoglobin
What will best measure oxygenation
- CBC hemoglobin as it measure oxygen and hemoglobin
Signs and symptoms of hypoxia
- cyanosis - central vs peripheral
- tachycardia/arrhythmias
- peripheral vasoconstriction
- poor judgement/motor incoordination/slow reaction time
- restlessness/agitation/confusion
- fatigue
How is tachycardia a sign or hypoxia
- to increase CO
- since you can’t pick up as much each “load” you need more loads
Central cyanosis vs peripheral cyanosis
- central: related to low oxygen and seen around the lips, tongue, nail beds (mucus membranes where capillary beds are close to the surface
- Peripheral: poor perfusion ie during cold air
How to assess oxygenation status
- indirect: assessment of oxygen saturation of the blood (pulse oximetry)
- direct: sampling of arterial blood (ABGs)
SpO2
- measures oxygen saturation indirectly via pulse oximeter
- LED that detects the absorption of red light
- impacted by cold hands, nail polish, hypoxia, device malfunction, darker skin
SaO2
- measures oxygen saturation directly from blood sample
- ABGs
PaO2
- partial pressure of oxygen (mmHg)
directly from a blood sample (ABG)
Oxygen saturation and partial pressure normal values and abnormal values
Normal:
- PaO2: 80-100 mmHg
- >95%
Mild hypoxia:
- 60-80 mmHg
- 90-95%
Moderate hypoxia:
- 40-60 mmHg
-80-90%
Severe hypoxia
- <40 mmHg
- <80% severe hypoxia
Oxyhemoglobin dissociation curve shifted to the right is caused by
- increased temperature (body)
- increased PCO2
- decreased pH
- O2 unloads quicker/decreased affinity for O2
Oxyhemoglobin dissociation curve that is shifted to the left is caused by
- decreased temperature
- decreased PCO2
- increased pH
- increased affinity for O2
Normal arterial blood gas values
1. PaO2:
2. PaCO2
3. pH
4. HCO3
4. SaO2 (oxygen saturation
- PaO2: 80-100 mmHg
- PaCO2: 35-45 mmHg
- pH: 7.35-7.45
- HCO3: 22-26
- SaO2 (oxygen saturation): 95-99%
Arterial blood gases/blood gas analysis - oxygenation
How is it done and what does it look at
- typically through A-line due to needing multiple measurements
- drive intervention + realists of intervention
Looks at: - Arterial pH
- PaCO2
- PaO2
- HCO3
- SaO2
- oxygenation status is determined by the PaO2 and oxygen saturation SaO2
When does hypoxemia occur
- when PaO2 is <60mmHG and SaO2/SpO2 <90%
- patient with resting SaO2/SpO2 <90% usually require supplemental oxygen during exertion to avoid further desaturation
Oxygen titration order
- MUST be prescribed by an MD
- Can only function within the MD’s orders
- DO NOT increase oxygen without an order
Arterial blood gases/blood gas analysis of acid base
- arterial pH
- PaCO2
- PaO2
- HCO3
- Oxygen saturation
- acid base balance determined by pH, bicarbonate and PaCO2
Acidic state vs alkalotic state
- acidic state exists from TOO much CO2 or too little HCO3
- alkaloid state can exist from either TOO little CO2 or too much HCO3
Acidosis/acidemia
- pH <7.4
- decreased bicarbonate = metabolic acidosis
- increase PaCO2 = respiratory acidosis (aka, alveolar hypoventilation or hypercapnia)
Alkalosis/alkalemia
- pH >7.4
- increase bicarbonate = metabolic alkalosis
- decreased PaCO2 = respiratory alkalosis (aka - alveolar hyperventilation or hypocapnia)
Metabolic acidosis: what and how
- pH<7.4; HCO3 decreased
- acid accumulation from metabolic processes or loss of HCO3
causes: - ketoacidosis
- lactic acidosis
- renal failure
- diarrhea (excrete bases)
Metabolic acidosis signs and symptoms
- lethargy
- confusion
- headahce
- nausea
- vomiting
metabolic acidosis treatment
- monitor and treat underlying cause
Metabolic alkalosis: what and how
- pH>7.4 or increase in HCO3
- acid loss or gain of too much base
causes: - acid loss due to vomiting
- ingestion of alkali (antacids)