Heart failure Flashcards
Causes of cardiac muscle dysfunction
- HTN
- CAD
- Cardiac dysrhythmias
- renal insufficiency
- cardiomyopathy
- heart valve abnormality
- pericardial effusion
- pulmonary embolism
- pulmonary HTN
- spinal cord injury
- age-related changes
Heart failure
- chronic progressive condition
- heart muscle is unable to pump enough blood to meet needs for blood and oxygen
- heart failure usually results in an enlarged heart
Heart failure typical path
- normal: ventricles fill with blood and then pump out about 70% of the blood
- diastolic dysfunction: the stiff ventricles fill with less blood and then pump out 70% but this is less than normal
- systolic dysfunction: enlarged ventricles fill with blood and then pump out 40-50% of the blood
What does dysfunction in the heart eventually cause
What does it impact first and then what happens from there?
- first impacts SV and EF
- chronic elevation of pressures will be transmitted up the atria into the vascular system
- the increase pressure leads to transudate of fluid from the vessels to the interstitial spaces of the lungs or peripheral tissue
- leads to edema
Classifications of heart failure
- right heart failure = peripheral edema
- left heart failure = pulmonary edema
- biventricular
- systolic vs diastolic dysfunction
heart failure with reduced ejection fracture
- EF<40
- systolic dysfunction
heart failure with preserved EF >50%
- still denotes lower than normal SV
- diastolic dysfunction
Right sided heart failure typical presentation
- congestion of peripheral tissues
- dependent edema and ascites (fluid in abdomen)
- GI tract congestion = anorexia, GI distress, weight loss
- liver congestion: signs related to impaired liver function
left sided heart failure presentation
- decreased CO: activity intolerance and signs of decreased tissue perfusion
- pulmonary congestions: impaired gas exchange (cyanosis and hypoxia) and pulmonary edema (cough with frothy sputum, orthopnea, PND)
What does pulmonary edema sound like
- crackles
- wet = gurgling
- dry = fire burning
what sound is expected with CHF
- S3
pulse pressure related to CHF
- normal = 40 (120-80)
- CHF: systolic decreases and diastolic increases leading to a lower pulse pressure
- indication heart is not functioning
Look at Left and right -sided heart failure diagram
- look
Clinical manifestations of left sided heart failure
- fatigue and weakness
- poor tolerance to activity
- progressive dyspnea
- orthopnea and PND
- tachypnea, pallor, cyanosis
- crackles or rales
- adventitious heart sounds (s3)
- hypoxia/hypercapnia
- voice sounds consistent with consolidation/infiltrates
- decrease pulse pressure
- weak pulse
clinical manifestations of right sided heart failure
- fatigue and weakness/poor tolerance to activity
- dependent peripheral edema/ascites
- weight gain (fluid)
- cold, pale and cyanotic extremities
- JVD
- decreased peripheral and ventilatory muscle strength and endurance
- poor activity/exercise tolerance or physical work capacity
- decreased quality of life/disability
Clinical diagnosis of CHF
- echocardiography: left ventricular EF, structure of LV, other structural abnormalities
- lab findings: elevated BNP, BUN, hematologic changes (increase RBCs), hypoxia/hypercapnia, changes in liver and electrolyte levels
- radiologic findings: Evaluation of size and shape of cardiac silhouette; presence of interstitial, perivascular, alveolar edema (fluid in lungs)
NYHA classification of CHF
- class 1: no limitation of physical activity
- class 2: slight limitation of physical activity, comfortable at rest
- class 3: marked limitation of physical activity, comfortable at rest (may have dyspnea at rest)
- class 4: inability to carry any physical activity with discomfort, symptoms present even at rest
ACC/AHA stages of CHF
- Stage A: high risk for developing CHF, no structural disorder to heart
- stage B: structural disorder or heart, never developed symptoms of CHF
- Stage C; past or current symptoms of CHF, symptoms associated with underlying heart disease
- stage D: end-stage disease, requires specialized treatment strategies
describe the CHF cycle
- initially may have impaired cardiac function but have CO sufficient for activity
THEN
- As HF progresses may decompensated with less tolerance to activity
- this can become a long term cycle of compensated then uncompensated
Ability of pump or accept blood depends on
- total blood volume
- body position and gravity
- skeletal muscle pump
- intrathoracic pressure
- atrial contribution to ventricular filling
- venous tone
- intrapericardial pressures
associated effects of CHF
On differnet systems
- pulmonary: back up of blood and pressures
- biochemical/nutritional: anorexia
- renal: sodium and fluid retention
- MSK: decrease blood flow, muscle atrophy
- hematological: abnormal blood cell function and increase blood volume
- pancreatic: impaired insulin and glucose imbalance
- hepatic: hypo fusion and/or venous congestion leading to cirrhosis
- neurochemical: increase sympathetic stimulation
HF impact on the heart
- stretching of the myocardium with increase ventricular EDV
- contractile state of myocardium declines
How can the kidneys contribute to the progression of CHF
- sense low arterial blood flow
- intiate a process to retain fluid
- this contributes to CHF
Pulmonary edema and its relation heart failure
- left ventricle cannot handle overload of blood volume
- pressure increases in the pulmonary vasculature
- fluid moves out of the pulmonary capillaries into the interstitial space of lungs and alveoli
Stage 1 of pulmonary edema in relation to left sided heart failure
- excessive fluid is present but managed by lymphatic system
- pressures are starting to increase
Stage 2 of pulmonary edema in relation to left sided heart failure
- characterized by the presence of interstitial edema
- increases in pressure causes the fluid to move into the interstitial space
- dry crackles with lung sounds
Stage 3 pulmonary edema in relation to left sided heart failure
- characterized by the presence of alveolar edema
- invades the parenchyma
- fluid overload
- compromised gas exchange
- wet crackles with lung sounds
- blood twinged sputum
Cardiogenic causes of pulmonary edema
- left ventricular failure
- HTN
- cardiomyopathy
non-cardiogenic causes of pulmonary edema
- smoke or toxin inhalation
- idiopathic pulmonary HTN
- sepsis/pneumonia (increase permeability)
- near drowning (inhaling water)
intrapulmonary shunt
- hypoxic blood
- O2 goes out of the alveoli normally
- with a fluid filled alveoli there is not as much gas exchange and therefore the it is perfused by not ventilated
Medical treatment for pulmonary edema
- manage HTN and CAD
- diet, nutrition, fluid management
- sometimes given a set amount of water to drink so they do not increase fluid too mcc
- proper prescription of activity (too high can cause fluid overload)
- medications
- mechanical/surgical intervention
- education and disease self-management is key
Management of heart failure
- directed at underlying causes or cause - HTN, atherosclerosis, ischemia, valve dysfunction, arrhythmia etc.
What are the goals when managing heart failure
- improve heart pump
- reduce the workload for the heart
- control sodium intake and water retention
- supplement vitamins, minerals and amino acids
- decrease sodium intake
- fluid restrictions
- eating heart healthy foods with low cholesterol and fat
Medication that patients with heart failure may be on
- diuretics: lassie, thiazides to eliminate fluids
- vasodilators: nitrates to decrease PVR
- ACE inhibitors: prevent vasoconstriction
- beta blockers: decreases sympathetic stimulation
- positive inotropic drugs: increase contractility
Look over management diagrams in lecture slides and understand where each comes into play
Mechanical/surgical management for CHF
- cardiac assistive devices (pacemakers/defibrillators)
- cardiac transplant
- assisted circulation (mechanical circulatory derives - MCD’s)
examples of assisted circulation devices
- intra-aortic ballon pump (can go home with this)
- extra corporal membrane oxygenation
- ventricular assist device
Life vest
- external cardiac defibrillator
- these people are waiting for other treatment such as transplant
transplantation
- if you work with these patients you are working in a specific center
Intra-aortic ballon pump
- systole: deflation to decrease after load, decrease cardiac work, decrease myocardial oxygen consumption and increase CO
- diastole: inflation: augmentation of diastolic pressure, increase coronary perfusion, allows more blood flow to the heart
- inserted through femoral artery
Extra corporal membrane oxygenation (ECMO)
- not going home with this
- waiting to get LVAD or transplant
- gives heart and lungs a break
- ECMH manages all the blood
- femoral access - try to avoid this as it limits mobility
- commonly used with premature babies since they don’t have surfactant
Ventricular assist devices
- can be left or right or biventrcualr
- heart can rest
- blood gets sucked or pumped out of the ventricle
- LVAD = left ventricular assistive device
Bridge vs destination therapy with HF
- bridge is that the LVAD or ECMO is bridging them to the next step
- destination therapy is the last thing they are doing
Education and self management techniques for patients with CHF
- assist with patient with taking responsibility for health (monitoring weight and symptoms)
- optimization of medical therapy/consistency with meds
- vigilant management and follow up
- exercise monitoring during and next day/next treatment
- early attention to fluid overload