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Endocrinology > Physiology I > Flashcards

Physiology I Flashcards

1
Q

What anterior pituitary hormones does Thyroid Releasing hormone (TRH) stimulate?

A

TSH, prolactin (p.289)

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2
Q

What anterior pituitary hormone does Dopamine inhibit?

A

Prolactin (p.289)

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3
Q

What anterior pituitary hormones does Corticotropic Releasing hormone (CRH) stimulate?

A

ACTH, Melanocyte stimulating hormone, B-endorphin (p.289)

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4
Q

What anterior pituitary hormone does Growth Hormone Releasing Hormone (GHRH) stimulate?

A

Growth Hormone (p.289)

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5
Q

What anterior pituitary hormones does Somatostatin inhibit?

A

GH, TSH (p.289)

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6
Q

What anterior pituitary hormones does Gonadotropin Releasing Hormone (GnRH) stimulate?

A

FSH, LH (p.289)

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7
Q

What hypothalamic hormone does prolactin inhibit?

A

GnRH (p.289)

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8
Q

From where is prolactin secreted?

A

Anterior pituitary (p.290)

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9
Q

What are the functions of prolactin?

A

Stimulates milk production in breast; inhibits ovulation in females and spermatogenesis in males (p.290)

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10
Q

How does prolactin inhibit ovulation and spermatogenesis?

A

By inhibiting GnRH synthesis and release (p.290)

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11
Q

How is prolactin secretion regulated?

A

Secretion from anterior pituitary is tonically inhibited by dopamine from the hypothalamus (p.290)

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12
Q

How does prolactin inhibit its own secretion?

A

By increasing dopamine synthesis and secretion from the hypothalamus (p.290)

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13
Q

What hormone stimulates prolactin secretion?

A

TRH (p.290)

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14
Q

What class of drugs can be used to treat prolactinomas?

A

Dopamine agonists (bromocriptine) (p.290)

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15
Q

What class of drugs stimulate prolactin secretion?

A

Dopamine antagonists (most antipsychotics) and estrogens (OCPs, pregnancy) (p.290)

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16
Q

From where is growth hormone (somatotropin) secreted?

A

Anterior pituitary (p.290)

17
Q

What is the function of growth hormone?

A

To stimulate linear growth and muscle mass through IGF-1/somatomedin secretion (p.290)

18
Q

What is the effect of growth hormone on insulin?

A

GH increases insulin resistance and is a diabetogenic (p.290)

19
Q

How is GH release regulated?

A

Released in pulses in response to GHRH (p.290)

20
Q

What increases GH secretion?

A

Exercise, sleep (p.290)

21
Q

What decreases GH secretion?

A

Glucose, somatostatin (p.290)

22
Q

What is a common cause of excess GH secretion?

A

Pituitary adenoma (p.290)

23
Q

What does excess GH secretion in adults cause?

A

Acromeagly (p.290)

24
Q

What does excess GH secretion in children cause?

A

Giagantism (p.290)

Endocrinology (26 decks)

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