Hypothalamic/ Pituitary Drugs Flashcards
Name the four hypothalamic/ pituitary drugs.
GH, Somatostain (octreotide), Oxytocin, ADH (desmopressin) (p.306)
What are the clinical uses for GH?
GH deficiency, Turner syndrome (p.306)
What are the clinical uses for Somatostatin (octreotide)?
Acromeagly, carcinoid, gastrinoma, glucagonoma, esophageal varices (p.306)
What are the clinical uses for Oxytocin?
Stimulates labour, uterine contractions, milk let down, controls uterine hemorrhage (p.306)
What are the clinical uses for ADH (desmopressin)?
Pituitary DI (central, not nephrogenic) (p.306)
What is the mechanism of action of Demeclocycline?
ADH antagonist (p.306)
To which drug family does demeclocycline belong?
Tetracycline family (p.306)
What is the clinical use for demeclocycline?
SIADH (p.306)
What toxicities are associated with demeclocycline?
Nephrogenic DI, photosensitivity, abnormalities of the bones and teeth (p.306)