Hypothalamic/ Pituitary Drugs Flashcards

1
Q

Name the four hypothalamic/ pituitary drugs.

A

GH, Somatostain (octreotide), Oxytocin, ADH (desmopressin) (p.306)

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2
Q

What are the clinical uses for GH?

A

GH deficiency, Turner syndrome (p.306)

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3
Q

What are the clinical uses for Somatostatin (octreotide)?

A

Acromeagly, carcinoid, gastrinoma, glucagonoma, esophageal varices (p.306)

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4
Q

What are the clinical uses for Oxytocin?

A

Stimulates labour, uterine contractions, milk let down, controls uterine hemorrhage (p.306)

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5
Q

What are the clinical uses for ADH (desmopressin)?

A

Pituitary DI (central, not nephrogenic) (p.306)

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6
Q

What is the mechanism of action of Demeclocycline?

A

ADH antagonist (p.306)

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7
Q

To which drug family does demeclocycline belong?

A

Tetracycline family (p.306)

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8
Q

What is the clinical use for demeclocycline?

A

SIADH (p.306)

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9
Q

What toxicities are associated with demeclocycline?

A

Nephrogenic DI, photosensitivity, abnormalities of the bones and teeth (p.306)

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