Phys 48-49: Sensations Flashcards
Meissners corpuscle
Type Αβ myelinated sensory fiber
Sensitive to movement over skin and low frequency vibrations
Rapid adaptation
Merkel’s disks
aka expanded tip receptor
Continous touch
Initially strong but then weak continous signal
type Aβ myelinated nerve fiber
Hair end organ
Detects hair movement
Ruffinis endings
Prolonged heavy touch and pressure
Pacini corspuscle
Vibration (rapid)
Adapt quickly
Free nerve ending fiber type
Aδ
slow af
Also type C for tickling sense
Tickle and itch detected by
Free nerve endings
Sensory info enters spinal cord through
Dorsal root of spinal nerve
Dorsal column/medial lemniscal transmits
Discriminative touch, proprioception
Anterolateral system transmits (spinothalmic)
Pain, thermal, crude touch, tickle, itch, sex
Bilateral excision of somatosensory area 1 symptoms
cannot judge characteristics of touch, just crude parts
somatosensory association areas numbers
5 and 7
Anterolateral column crosses at
Level of spinal cord root
Dorsal column crosses at
lower medulla
Spinothalmic tracts aka
anterior/lateral tracts
Pain resulting from heat correlates to
RATE of tissue damage destruction
Fast pain fibers
Aδ
slow pain fibers
C
Fast pain tract
Neospinothalmic
Slow pain tract
Paleospinothalmic
Neurotransmitter of Aδ nerve fibers
Glutamate
Type C nerve fiber neuro transmitter
Substance P
Slow pain ends up in
Reticular system (no sleep when pain)
Cordotomy
Spinothalmic tract is cut to reduce pain. Lasts a few months before other tracts take over
3 parts of anlgesia system
Periventricular/Periaquedutal
Raphe magnus nucleus/ Nucleus reticularis
Pain inhibitiroy complex in dorsal horns of cord
Enkaphalin
AKA endogenous opiate in brain and spinal cord
Endorphin
Endogenous opiate in hypothalmus and pituitary
Visceral pain transmitted by ____ fibers
C
Why is parietal pain localized
follows parietal tract
(think pleuritic chest pain)
What stimulates pain nerve endings in ischemia
Bradykinin, proteolytic enzymes
Parietal vs visceral pain
Parietal is sharp
Visceral is dull
Hyperalgesia primary vs secondary
Primary: nerve endings too sensitive (eg sunburn)
Secondary: Too much transmission (seen on spinal or thalmic lesions)
Herpes zoster shingles affects
A single DRG
Tic douloreux
Stabbing pain in face (trigeminal or glossopharyngeal)
Causes by mechanorecptors, not pain nerve endings
Brown-Sequard syndrome
Transection of half of spinal cord
flacid paralysis at level of injury
Ipsilateral loss of discriminative touch and proprioception
Contralateral pain and thermal loss
Cerebral vault headache location
Front
Brainstem and cereballar vault headache location
back
Headache of meningitis felt over
entire head
Alcohol headache reasons
Alcohol is toxic and damages meninges
Dehydration exacerbates
Cold pain fiber range
less than 10 degrees C
Cold fiber range
10 C to 40C
Peaks at 24 C
Warm receptor range
30 C to 45 C
Heat pain receptor range
45 and up
also cold fibers due to damage