Path 24: Endocrine

Question 1

Anterior pituitary AKA

Answer 1

adenohypophysis

Question 2

Somatotrophs secrete

Answer 2

Growth hormone

Question 3

Mammosomatotrophs secrete

Answer 3

GH and prolactin

Question 4

Lactotrophs produces

Answer 4

Prolactin

Question 5

Corticotrophs produce

Answer 5

ACTH: adenocorticotropic hormone

Question 6

Thyrotrophs produce

Answer 6

Thyroid stimulating hormone

Question 7

Gonadotrophs produce

Answer 7

FSH, LH

Question 8

Posterior pituitary consists of modified _____ cells called _____ as well as __________

Answer 8

glial

pituicytes

axons from hypothalmus

Question 9

Hyperpituitarism arises from

Answer 9

Excess trophic hormone secretion

Question 10

Most common cause of hyperpituitarism

Answer 10

Adenoma arising in the anterior lobe of pituitary

Question 11

Most common alteration in pituitary adenoma

Answer 11

Activating G-protein mutation

Question 12

Most common type of hyperfunctioning pituitary adenoma

Answer 12

Prolactin-secreting lactotroph adenoma

Question 13

Prolactinemia symptoms

Answer 13

Amenorrhea

Galactorrhea

Loss of libido

Infertility

Question 14

Hypercortisolism aka

Answer 14

Cushing’s syndrome

Question 15

Nelson syndrome

Answer 15

Happens after removal of adrena glands.

Lack of negative inhibition causes coriticotrophs to increase in size and cause hypermelanin and mass effects.

No hypercorticolism bc lack of adrenal glands

Question 16

Growth hormone deficiency in children

Answer 16

Pituitary dwarfism

Question 17

Loss of LH and FSH results in

Answer 17

Amenorrhea, infertility, decreased libido

also pubic hair loss

Question 18

causes of Diabetes insipidus

Answer 18

ADH deficiency

V2 receptor mutation

Question 19

SIADH clinical manifestations

Answer 19

Hyponatremia, cerebral edema, neurodysfunction