PHARMACY REVIEW Flashcards

1
Q

Who can issue prescription drugs?

A

Written by an accredited authorized provider.

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2
Q

Controlled substances are ordered with what form?

A

DD 1289

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3
Q

what other form can non controlled meds be ordered on?

A

poly-prescription NAVMED 6710/6

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4
Q

what information is required to be written on a prescription?

A
patients full name
date prescription written
age or date of birth
full name of drug, form of drug, dosage size or strength
quantity dispensed
signa (patient directions no abbreviations)
provider signature
refill authorization
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5
Q

Can an IDC refill controlled drugs?

A

NO

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6
Q

define pharmacokinetic

A

activities of the drug after it enters the body. Includes absorption, distribution, metabolism, excretion

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7
Q

Define bioavailability

A

the percentage of the drug dose that reaches the systemic circulation

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8
Q

What factors alter bioavailability?

A
drug form
route
changes in liver metabolism
GI mucosa and motality
food and drugs
solubility
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9
Q

A patient with what condition may require a lower dose of a medication?

A

Liver disease

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10
Q

define pharmacodynamics and the two effects

A

the drugs actions and effect within the body

  • primary or desired effect
  • secondary or side effects; desired or undesired
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11
Q

Define Physical Dependence

A

a compulsive need to use a substance repeatedly to AVOID mild to severe withdrawal symtpoms

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12
Q

What is an Agonist

A

Drug that binds with a receptor to produce the

therapeutic response

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13
Q

What is Antagonist

A

Drug binds to receptor stronger than the

agonist thus producing no pharmacologic effect

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14
Q

What is a cumulative drug effect

A

A drug effect that occurs when the body has

not fully metabolized a dose of a drug before the next dose is given.

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15
Q

Describe an additive drug effect

A

when the combined

effect of two drugs is equal to the sum of each drug given alone.

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16
Q

Describe synergism

A

when drugs produce an effect that is greater than the sum of their separate actions.

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17
Q

Which factors affect the influence of a drug effect

A
  • Age
  • Weight
  • Gender
  • Disease
  • Route of administration
  • Drug use and pregnancy (CAT A+B safe)
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18
Q

What are the main routes of drug administration?

A

Oral
Parenteral
Skin/Mucus membrane

19
Q

What are the routes within Oral administration?

A

Nasogastric
Buccal
Sublingual

20
Q

What are the routes within Parenteral administration?

A

Subcutaneous
Intramuscular
Intravenous
Intradermal

21
Q

What are the routes within skin/mucus membrane administration?

A

Topical
Transdermal
Inhalation

22
Q

Which administration route offers an almost immediate effect

A

IV

23
Q

Which route of administration offers a systemic effect

A

Transdermal

24
Q

Which route of administration offers a LOCAL effect on the lungs

A

inhalation

25
Q

What action does sedatives and hypnotics have?

A

Long Lasting BARBITURATES

  • Anti Convulsive
  • Depress CNS
  • Produces drowsiness, sedation, and hypnosis
26
Q

What is an important patient education for Barbiturates

A

Educate on the effect of alcohol and medications

27
Q

What is an example of Bariturates?

A

Phenobarbital

28
Q

Anti-anxiety drugs can be separated in what subcategories

A

Benzodiazepines

Non- Benzodiazepines

29
Q

Give examples of benzodiazepines

A

End in PAM

  • Alprazolam
  • Diazepam
  • Lorazepam
30
Q

Give examples of non-benzodiazepams

A
  • Hydroxyzine

- Sertraline (SSRI)- may be used long term

31
Q

What are the subclasses of Anti-Depressants

A

TCA’s
MAOI’s
SSRI’s
SNRI’s

32
Q

What are the 1st generation Anti-depressants

A

TCA

MAOI

33
Q

What are the 2nd generation Anit-depressants

A

SSRI

34
Q

What is the action of SSRI’s

A

Increases serotonin by inhibiting neuron al uptake to the CNS

35
Q

Contraindications of TCA’s

A

co-administration with or within 14 days of MAOI’s

36
Q

Contraindications of MAOI’s

A
  • can cause serotonin syndrome
  • diet high in red wine or smoked meats/cheese
  • CHF
37
Q

Contraindications of Wellbutrin

A

contraindicated in patients with a seizure disorder

38
Q

what is an important patient education piece with Sertaline (SSRI) used with a MAOI

A

may result in a fatal reaction (serotonin syndrome)

39
Q

What is your first line Anti-depressant medications

A

SSRI

40
Q

What are some examples of SSRI’s

A

Mostly end in “ine”

  • Fluoxetine
  • Sertraline
  • Paroxetine
  • Citalopram
41
Q

What is the action of Anti-psychotics

A
  • block dopamine receptors in the brain**

- also alter dopamine release and turnover

42
Q

What are adverse effects of Anit-psychotics

A

Anticholinergic- dry mouth, hypotension, sedation, photophobia, photosensativity, and headache

43
Q

What as an example of Anti-psychiotics

A

Haloperidol

44
Q

What are amphetamines used for

A

treatment of Narcolepsy and ADHD