Pharmacovigilance & genetics Flashcards
1
Q
Define pharmacovigilance
A
identification, assessment and subsequent prevention of adverse drug reaction whilst optimising benefits
2
Q
What does thalidomide cause in a fetus?
A
phocomelia
3
Q
What is a type A adverse drug reaction?
A
Dose related, common and predictable
4
Q
What is a type B adverse drug reaction?
A
Not dose related, unpredictable, serious and need to stop treatment
5
Q
Define pharmacogenetics
A
How an individual gene may affect response to drug or drug response on body
6
Q
Person to person variability contributes to what % of ADRs?
A
7%
