Antibiotics Flashcards
1
Q
Gram positive vs gram negative
A
Gram positive has a thick peptidoglycan cell wall while gram negative has a thin layer
2
Q
How do beta lactams work?
A
Inhibit cell wall synthesis
3
Q
How does bacteria become resistant to a beta lactam?
A
Produces beta lactamase enzymes that break it down
4
Q
Time vs concentration dependent killing of bacteria?
A
time = long half life beneficial to spend longer at binding site concentration = need a certain concentration at binding site
5
Q
What is co-amoxiclav made of and why?
A
Clavulanic acid = inhibits effect of some beta lactamase enzymes, helps amoxicillin work better
Amoxicillin = acts on cell walls (beta lactam)
6
Q
Name an antiviral
A
Aciclovir
7
Q
What is the difference in trwating Herpes simplex virus in a standard patient vs immunocompromised patient?
A
Immunocompromised dose is double
