Cancer Chemotherapy Flashcards

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1
Q

What are the purines?

A

Adenine and guanine

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2
Q

What are the pyrimidines?

A

Cytosine and thymine

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3
Q

How many cells are needed to detect cancer?

A

10^9

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4
Q

What is the fractional cell kill hypothesis used for?

A

To calculate drug administration and dosing

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5
Q

What are the adverse effects of chemotherapy(due to effect of treatment of the cancer)?

A

acute renal failure, GI perforation, DIC

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6
Q

What does mucositis present with?

A

Sore mouth/throat, diarrhoea, GI bleed

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