Pharmacogenetics Flashcards

1
Q

3 Types of Genetic Variation Affecting Drug Response

A

Target prots (pharmacodynamics)
Enzymes that metabolize drugs (pharmacokinetics)
Variation in genes unrelated to drugs/metabolism - side effects (Idiosyncratic)

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2
Q

Candidate Gene Therapy

A

Genomic screening of a determined/common set of polymorphisms affecting drug therapy can allow clinicians to avoid unwanted drug interactions

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